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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'mGluR2 and G alpha 16' and Ligand = 'BDBM222989'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
mGluR2 and G alpha 16


(Homo sapiens (Human))
BDBM222989
PNG
(US9315518, 25-5)
Show SMILES CN1c2nc(ccc2N(CC2CC2(F)F)S1(=O)=O)C1CCCNC1
Show InChI InChI=1/C15H20F2N4O2S/c1-20-14-13(5-4-12(19-14)10-3-2-6-18-8-10)21(24(20,22)23)9-11-7-15(11,16)17/h4-5,10-11,18H,2-3,6-9H2,1H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 359n/an/an/an/a



Merck Sharp & Dohme Corp.

US Patent


Assay Description
The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...


US Patent US9315518 (2016)


BindingDB Entry DOI: 10.7270/Q2G44P5C
More data for this
Ligand-Target Pair