Compile Data Set for Download or QSAR

Found 4 hits of ec50 for monomerid = 101309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM101309 (US9695151, 3 | US9695151, 4) Show SMILES CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C.CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |@:10,@@:41| Show InChI InChI=1S/2C22H27ClN4O3S/c2*1-5-31(29,30)26-9-8-16(14-26)25(4)17-11-18(13-24-12-17)27-21(28)19-7-6-15(23)10-20(19)22(27,2)3/h2*6-7,10-13,16H,5,8-9,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695151 (2017) BindingDB Entry DOI: 10.7270/Q2KD1W22
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM101309 (US9695151, 3 | US9695151, 4) Show SMILES CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C.CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |@:10,@@:41| Show InChI InChI=1S/2C22H27ClN4O3S/c2*1-5-31(29,30)26-9-8-16(14-26)25(4)17-11-18(13-24-12-17)27-21(28)19-7-6-15(23)10-20(19)22(27,2)3/h2*6-7,10-13,16H,5,8-9,14H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	124	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695151 (2017) BindingDB Entry DOI: 10.7270/Q2KD1W22
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM101309 (US9695151, 3 | US9695151, 4) Show SMILES CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C.CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |@:10,@@:41| Show InChI InChI=1S/2C22H27ClN4O3S/c2*1-5-31(29,30)26-9-8-16(14-26)25(4)17-11-18(13-24-12-17)27-21(28)19-7-6-15(23)10-20(19)22(27,2)3/h2*6-7,10-13,16H,5,8-9,14H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695151 (2017) BindingDB Entry DOI: 10.7270/Q2KD1W22
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM101309 (US9695151, 3 | US9695151, 4) Show SMILES CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C.CCS(=O)(=O)N1CCC(C1)N(C)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |@:10,@@:41| Show InChI InChI=1S/2C22H27ClN4O3S/c2*1-5-31(29,30)26-9-8-16(14-26)25(4)17-11-18(13-24-12-17)27-21(28)19-7-6-15(23)10-20(19)22(27,2)3/h2*6-7,10-13,16H,5,8-9,14H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	188	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co...				US Patent US9695151 (2017) BindingDB Entry DOI: 10.7270/Q2KD1W22
					More data for this Ligand-Target Pair