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Compile Data Set for Download or QSAR

Found 2 hits of kd for monomerid = 102152   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Orexin receptor type 2


(Homo sapiens (Human))
BDBM102152
PNG
(US8530648, 49)
Show SMILES O=C1N(Cc2cccc(c2)-c2ccccc2)CCCC11CCN(CC1)c1cnc2ccccc2n1
Show InChI InChI=1S/C30H30N4O/c35-29-30(15-18-33(19-16-30)28-21-31-26-12-4-5-13-27(26)32-28)14-7-17-34(29)22-23-8-6-11-25(20-23)24-9-2-1-3-10-24/h1-6,8-13,20-21H,7,14-19,22H2
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PC cid
PC sid
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Similars

US Patent
n/an/an/a 59n/an/an/a7.5n/a



Novartis AG

US Patent


Assay Description
Radioligand binding assay using orexin receptor.


US Patent US8530648 (2013)


BindingDB Entry DOI: 10.7270/Q2SB44DR
More data for this
Ligand-Target Pair
Orexin/Hypocretin receptor type 1


(Homo sapiens (Human))
BDBM102152
PNG
(US8530648, 49)
Show SMILES O=C1N(Cc2cccc(c2)-c2ccccc2)CCCC11CCN(CC1)c1cnc2ccccc2n1
Show InChI InChI=1S/C30H30N4O/c35-29-30(15-18-33(19-16-30)28-21-31-26-12-4-5-13-27(26)32-28)14-7-17-34(29)22-23-8-6-11-25(20-23)24-9-2-1-3-10-24/h1-6,8-13,20-21H,7,14-19,22H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/an/a 1.32E+3n/an/an/a7.5n/a



Novartis AG

US Patent


Assay Description
Radioligand binding assay using orexin receptor.


US Patent US8530648 (2013)


BindingDB Entry DOI: 10.7270/Q2SB44DR
More data for this
Ligand-Target Pair