Compile Data Set for Download or QSAR

Found 5 hits of ki for monomerid = 103761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM103761 (US8551978, I-30 | US8816088, I-30 | US9394275, I-3...) Show SMILES CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(c1)C(=O)Nc1cc(C)c(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1C |r| Show InChI InChI=1S/C49H52N6O7/c1-31-27-42(32(2)26-35(31)29-50-30-44(57)39-16-18-43(56)47-40(39)17-19-45(58)53-47)51-48(60)34-12-9-13-36(28-34)54(3)46(59)22-25-55-23-20-37(21-24-55)62-49(61)52-41-15-8-7-14-38(41)33-10-5-4-6-11-33/h4-19,26-28,37,44,50,56-57H,20-25,29-30H2,1-3H3,(H,51,60)(H,52,61)(H,53,58)/t44-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance, Inc. US Patent					Assay Description Radioligand binding assay using muscarinic receptors.				US Patent US8551978 (2013) BindingDB Entry DOI: 10.7270/Q2Q81BPC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM103761 (US8551978, I-30 | US8816088, I-30 | US9394275, I-3...) Show SMILES CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(c1)C(=O)Nc1cc(C)c(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1C |r| Show InChI InChI=1S/C49H52N6O7/c1-31-27-42(32(2)26-35(31)29-50-30-44(57)39-16-18-43(56)47-40(39)17-19-45(58)53-47)51-48(60)34-12-9-13-36(28-34)54(3)46(59)22-25-55-23-20-37(21-24-55)62-49(61)52-41-15-8-7-14-38(41)33-10-5-4-6-11-33/h4-19,26-28,37,44,50,56-57H,20-25,29-30H2,1-3H3,(H,51,60)(H,52,61)(H,53,58)/t44-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Respiratory Company, LLC US Patent					Assay Description Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 uL. CHO cell me...				US Patent US8816088 (2014) BindingDB Entry DOI: 10.7270/Q2TQ6068
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM103761 (US8551978, I-30 | US8816088, I-30 | US9394275, I-3...) Show SMILES CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(c1)C(=O)Nc1cc(C)c(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1C |r| Show InChI InChI=1S/C49H52N6O7/c1-31-27-42(32(2)26-35(31)29-50-30-44(57)39-16-18-43(56)47-40(39)17-19-45(58)53-47)51-48(60)34-12-9-13-36(28-34)54(3)46(59)22-25-55-23-20-37(21-24-55)62-49(61)52-41-15-8-7-14-38(41)33-10-5-4-6-11-33/h4-19,26-28,37,44,50,56-57H,20-25,29-30H2,1-3H3,(H,51,60)(H,52,61)(H,53,58)/t44-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Respiratory Company LLC US Patent					Assay Description compounds were performed with [3H]NMS at 1 nM and eleven different test compound concentrations. The test compounds were initially dissolved to a con...				US Patent US9572802 (2017) BindingDB Entry DOI: 10.7270/Q2VH5QWS
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM103761 (US8551978, I-30 | US8816088, I-30 | US9394275, I-3...) Show SMILES CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(c1)C(=O)Nc1cc(C)c(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1C |r| Show InChI InChI=1S/C49H52N6O7/c1-31-27-42(32(2)26-35(31)29-50-30-44(57)39-16-18-43(56)47-40(39)17-19-45(58)53-47)51-48(60)34-12-9-13-36(28-34)54(3)46(59)22-25-55-23-20-37(21-24-55)62-49(61)52-41-15-8-7-14-38(41)33-10-5-4-6-11-33/h4-19,26-28,37,44,50,56-57H,20-25,29-30H2,1-3H3,(H,51,60)(H,52,61)(H,53,58)/t44-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Respiratory Company, LLC US Patent					Assay Description Radioligand binding assays for cloned muscarinic receptors were performed in 96-well microtiter plates in a total assay volume of 100 μL. CHO ce...				US Patent US9682957 (2017) BindingDB Entry DOI: 10.7270/Q23776WR
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM103761 (US8551978, I-30 | US8816088, I-30 | US9394275, I-3...) Show SMILES CN(C(=O)CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)c1cccc(c1)C(=O)Nc1cc(C)c(CNC[C@H](O)c2ccc(O)c3[nH]c(=O)ccc23)cc1C |r| Show InChI InChI=1S/C49H52N6O7/c1-31-27-42(32(2)26-35(31)29-50-30-44(57)39-16-18-43(56)47-40(39)17-19-45(58)53-47)51-48(60)34-12-9-13-36(28-34)54(3)46(59)22-25-55-23-20-37(21-24-55)62-49(61)52-41-15-8-7-14-38(41)33-10-5-4-6-11-33/h4-19,26-28,37,44,50,56-57H,20-25,29-30H2,1-3H3,(H,51,60)(H,52,61)(H,53,58)/t44-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	-13.8	n/a	n/a	n/a	n/a	n/a	n/a	37
Theravance Respiratory Company, LLC US Patent					Assay Description Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...				US Patent US9394275 (2016) BindingDB Entry DOI: 10.7270/Q2NS0SS8
					More data for this Ligand-Target Pair