Compile Data Set for Download or QSAR

Found 8 hits of ic50 for monomerid = 104217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.80	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10.8	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19.4	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	482	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM104217 (US8575145, 125 | US8575145, 126 | US8575145, 127 |...) Show SMILES FC1CNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12 Show InChI InChI=1S/C20H18FN5O/c21-14-12-22-10-9-16(14)27-17-5-3-4-13-7-8-15(23-19(13)17)20-25-24-18-6-1-2-11-26(18)20/h1-8,11,14,16,22H,9-10,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	22
Array BioPharma Inc. US Patent					Assay Description The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...				US Patent US8575145 (2013) BindingDB Entry DOI: 10.7270/Q2M90797
					More data for this Ligand-Target Pair