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Compile Data Set for Download or QSAR

Found 3 hits of kd for monomerid = 10857   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM10857
PNG
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)
Show SMILES Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/an/a 5.55E+3n/an/an/an/an/a



Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Binding affinity to GST-fused human carbonic anhydrase-2 expressed in Escherichia coli BL21 codon plus cells assessed as dissociation constant by SPR...


J Med Chem 59: 4245-56 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01643
BindingDB Entry DOI: 10.7270/Q2PV6NB2
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Protein argonaute-2


(Homo sapiens)
BDBM10857
PNG
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)
Show SMILES Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
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PC cid
PC sid
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Article
PubMed
n/an/an/a 1.70E+4n/an/an/an/an/a


TBA

Assay Description
Binding affinity to human Argonaut protein 2 PAZ domain assessed as dissociation constant by using isothermal titration microcalorimetry


Citation and Details

Article DOI: 10.1016/j.bmcl.2020.127637
BindingDB Entry DOI: 10.7270/Q2HQ43H0
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Bos taurus)
BDBM10857
PNG
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)
Show SMILES Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 5.88E+3n/an/an/an/an/a



Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Binding affinity to bovine carbonic anhydrase-2 assessed as dissociation constant by SPR method


J Med Chem 59: 4245-56 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01643
BindingDB Entry DOI: 10.7270/Q2PV6NB2
More data for this
Ligand-Target Pair