Compile Data Set for Download or QSAR

Found 8 hits of ki for monomerid = 11352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Collagenase ColG (Clostridium histolyticum)	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Bos taurus (bovine))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM11352 (Hydroxamate 33 | N-hydroxy-2-[(4-methoxybenzene)[(...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccccc1N(=O)=O Show InChI InChI=1S/C16H17N3O7S/c1-26-13-6-8-14(9-7-13)27(24,25)18(11-16(20)17-21)10-12-4-2-3-5-15(12)19(22)23/h2-9,21H,10-11H2,1H3,(H,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	>200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi					Assay Description Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...				J Med Chem 43: 3677-87 (2000) Article DOI: 10.1021/jm000027t BindingDB Entry DOI: 10.7270/Q2736P45
					More data for this Ligand-Target Pair