Compile Data Set for Download or QSAR

Found 7 hits of ic50 for monomerid = 113589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	7.4	37
Galderma Research & Development US Patent					Assay Description The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...				US Patent US8633196 (2014) BindingDB Entry DOI: 10.7270/Q2KK99FQ
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	7.4	37
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9 (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM113589 (US8633196, 19 | US9365529, 19) Show SMILES CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO Show InChI InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair