Compile Data Set for Download or QSAR

Found 7 hits of ic50 for monomerid = 113590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.4	37
Galderma Research & Development US Patent					Assay Description The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...				US Patent US8633196 (2014) BindingDB Entry DOI: 10.7270/Q2KK99FQ
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	7.4	37
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	887	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9 (Homo sapiens (Human))	BDBM113590 (US8633196, 21 | US9365529, 21) Show SMILES Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 Show InChI InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVLOPMENT US Patent					Assay Description The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...				US Patent US9365529 (2016) BindingDB Entry DOI: 10.7270/Q29W0DC8
					More data for this Ligand-Target Pair