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Compile Data Set for Download or QSAR

Found 1 hit of kd for monomerid = 12915   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform


(Homo sapiens (Human))
BDBM12915
PNG
(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
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MMDB

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Article
PubMed
n/an/a 1.40E+3 210n/an/an/a7.220



MRC



Assay Description
Binding was detected as a change in the intrinsic tryptophan fluorescence of the PI3K upon the addition of inhibitor. The inhibitor was incubated wit...


Mol Cell 6: 909-19 (2000)


Article DOI: 10.1016/s1097-2765(05)00089-4
BindingDB Entry DOI: 10.7270/Q22F7KPC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)