Compile Data Set for Download or QSAR

Found 29 hits of ic50 for monomerid = 136055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US8853203 (2014) BindingDB Entry DOI: 10.7270/Q2MP520T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	153	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	561	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	672	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	687	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	702	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	814	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US8853203 (2014) BindingDB Entry DOI: 10.7270/Q2MP520T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM136055 (US8853203, 99 | US9650377, Example 99s) Show SMILES Fc1ccc(c(F)n1)-c1cccc2C3=CC(=NCC(=O)N3CCc12)n1cnc(c1)C1CC1 |c:16,t:14| Show InChI InChI=1S/C24H19F2N5O/c25-21-7-6-18(24(26)29-21)15-2-1-3-17-16(15)8-9-31-20(17)10-22(27-11-23(31)32)30-12-19(28-13-30)14-4-5-14/h1-3,6-7,10,12-14H,4-5,8-9,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...				US Patent US9650377 (2017) BindingDB Entry DOI: 10.7270/Q2G73GT2
					More data for this Ligand-Target Pair