Compile Data Set for Download or QSAR

Found 15 hits of ki for monomerid = 164065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	37	-9.42	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	37	-9.42	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM001525) or Chinese ovary cells (CHO) s...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	37	-9.42	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	57	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	57	-9.18	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	57	-9.18	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	325	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	325	-9.29	n/a	n/a	n/a	n/a	n/a	n/a	40
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	325	-9.29	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	325	-9.29	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164065 (US9062078, 195 | US9475819, 195 | US9637496, 379 |...) Show SMILES Cc1ccc(-c2ncccn2)c(n1)C(=O)N1C2CCC1C(C2)Nc1ccc(cn1)C(F)(F)F |TLB:22:20:18.17:15| Show InChI InChI=1S/C23H21F3N6O/c1-13-3-6-16(21-27-9-2-10-28-21)20(30-13)22(33)32-15-5-7-18(32)17(11-15)31-19-8-4-14(12-29-19)23(24,25)26/h2-4,6,8-10,12,15,17-18H,5,7,11H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	336	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair