Compile Data Set for Download or QSAR

Found 14 hits of ki for monomerid = 164076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20E+3	-7.50	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20E+3	-7.50	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20E+3	-8.48	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.50E+3	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.50E+3	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	40
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.50E+3	-8.34	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-7.16	n/a	n/a	n/a	n/a	n/a	n/a	40
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-7.16	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-6.34	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164076 (US9062078, 206 | US9475819, 231 | US9637496, 231 |...) Show SMILES COc1c(F)cccc1C(=O)N1C2CCC1C(C2)Nc1cnc2ccccc2n1 |TLB:18:16:14.13:11| Show InChI InChI=1S/C22H21FN4O2/c1-29-21-14(5-4-6-15(21)23)22(28)27-13-9-10-19(27)18(11-13)26-20-12-24-16-7-2-3-8-17(16)25-20/h2-8,12-13,18-19H,9-11H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-6.34	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair