Compile Data Set for Download or QSAR

Found 15 hits of ki for monomerid = 164080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	128	-9.87	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	128	-9.87	n/a	n/a	n/a	n/a	n/a	n/a	40
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	128	-9.87	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	211	-8.46	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	211	-8.46	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	211	-9.56	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% F...				US Patent US9062078 (2015) BindingDB Entry DOI: 10.7270/Q2RX99V3
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-7.16	n/a	n/a	n/a	n/a	n/a	n/a	40
JANSSEN PHARMACEUTICA NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat # SH30022), 10%...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-7.16	n/a	n/a	n/a	n/a	n/a	n/a	40
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hyclone, cat #SH30022), 10% ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9637496 (2017) BindingDB Entry DOI: 10.7270/Q24J0H68
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-6.34	n/a	n/a	n/a	n/a	n/a	n/a	4
JANSSEN PHARMACEUTICA NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9695183 (2017) BindingDB Entry DOI: 10.7270/Q2N58JHM
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Rattus norvegicus (Rat))	BDBM164080 (US9062078, 210 | US9475819, 235 | US9637496, 210 |...) Show SMILES FC(F)(F)c1ccnc(NC2CC3CCC2N3C(=O)c2ccccc2-n2nccn2)c1 |THB:9:10:14.13:16| Show InChI InChI=1S/C21H19F3N6O/c22-21(23,24)13-7-8-25-19(11-13)28-16-12-14-5-6-18(16)29(14)20(31)15-3-1-2-4-17(15)30-26-9-10-27-30/h1-4,7-11,14,16,18H,5-6,12H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	>-6.34	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_001525) or Chinese ovary cells (CHO) ...				US Patent US9475819 (2016) BindingDB Entry DOI: 10.7270/Q2DZ0771
					More data for this Ligand-Target Pair