Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-adenosylmethionine synthase isoform type-1/type-2 (Rattus norvegicus) | BDBM18134 (({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat Methionine adenosyltransferase was reported | J Med Chem 29: 318-22 (1986) BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthase isoform type-2 (Rattus norvegicus) | BDBM18134 (({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory constant against rat kidney Methionine adenosyltransferase II | J Med Chem 29: 318-22 (1986) BindingDB Entry DOI: 10.7270/Q2DF6RSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycine--tRNA ligase (Bombyx mori) | BDBM18134 (({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.00E+4 | -6.41 | 1.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Medical College of Ohio | Assay Description Aminoacyl-tRNA synthetase assays were measuring the incorporation of [14C] amino acid into tRNA. | Biochemistry 42: 5333-40 (2003) Article DOI: 10.1021/bi030031h BindingDB Entry DOI: 10.7270/Q2HQ3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycerol kinase (Homo sapiens (Human)) | BDBM18134 (({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article | 9.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its binding affinity against glycerol kinase (ATP competitive inhibition) | Bioorg Med Chem Lett 7: 2613-2616 (1997) Article DOI: 10.1016/S0960-894X(97)10051-8 BindingDB Entry DOI: 10.7270/Q2GF0V0S | |||||||||||
More data for this Ligand-Target Pair |