Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 20334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20334 (1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as blockade of acid-induced receptor activation by FLIPR assay				J Med Chem 50: 2589-96 (2007) Article DOI: 10.1021/jm060637e BindingDB Entry DOI: 10.7270/Q269737M
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20334 (1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonistic activity towards human vanilloid receptor subtype 1 expressed in HEK293 cell membrane, as inhibition of agonist-induced intracellular [C...				Bioorg Med Chem Lett 14: 3053-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.038 BindingDB Entry DOI: 10.7270/Q2FB52D6
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20334 (1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux				J Med Chem 51: 392-5 (2008) Article DOI: 10.1021/jm701007g BindingDB Entry DOI: 10.7270/Q218367F
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20334 (1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 assessed as inhibition of calcium influx				Bioorg Med Chem Lett 21: 1338-41 (2011) Article DOI: 10.1016/j.bmcl.2011.01.056 BindingDB Entry DOI: 10.7270/Q20K28W6
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20334 (1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as blockade of capsaicin-induced receptor activation by FLIPR assay				J Med Chem 50: 2589-96 (2007) Article DOI: 10.1021/jm060637e BindingDB Entry DOI: 10.7270/Q269737M
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM20334 (1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-ur...) Show SMILES FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as blockade of capsaicin-induced receptor activation by FLIPR assay				J Med Chem 50: 2589-96 (2007) Article DOI: 10.1021/jm060637e BindingDB Entry DOI: 10.7270/Q269737M
					More data for this Ligand-Target Pair