BindingDB PrimarySearch

Found 11 hits of kd for monomerid = 28422
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	7.5	5
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	8.20E+3	n/a	n/a	n/a	7.5	10
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.14E+4	n/a	n/a	n/a	7.5	15
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.66E+4	n/a	n/a	n/a	7.5	20
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	2.67E+4	n/a	n/a	n/a	7.5	25
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Met repressor (Escherichia coli)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Binding affinity to Escherichia coli metJ in presence of operator DNA complex by filter binding study				Bioorg Med Chem Lett 22: 278-84 (2011) Article DOI: 10.1016/j.bmcl.2011.11.017 BindingDB Entry DOI: 10.7270/Q2HQ40BH
University of Leeds Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.91E+4	n/a	n/a	n/a	7.5	4
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.07E+4	n/a	n/a	n/a	7.5	4
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	7.5	4
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Activity of human wild type PNMT assessed as phenylethanolamine methylation				J Med Chem 48: 7243-52 (2005) Article DOI: 10.1021/jm050568o BindingDB Entry DOI: 10.7270/Q2QC049M
University of Michigan Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	4.72E+4	n/a	n/a	n/a	7.5	4
Washington University					Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...				J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39
Washington University					More data for this Ligand-Target Pair