Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 3A/3B (Mus musculus (house mouse)) | BDBM50000483 ((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN) | Bioorg Med Chem Lett 2: 461-466 (1992) Article DOI: 10.1016/S0960-894X(00)80170-5 BindingDB Entry DOI: 10.7270/Q2H41SMM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 3A/3B (Mus musculus (house mouse)) | BDBM50000483 ((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cells | J Med Chem 33: 1594-600 (1990) BindingDB Entry DOI: 10.7270/Q25Q4X94 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |