Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50049186 ((S)-3-Methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bahcesehir University (BAU) Curated by ChEMBL | Assay Description Displacement of [125I-Sar1-Ile8]-Ang2 from human angiotensin 2 receptor type 1 receptor expressed in HEK293 cells after 1 hr by gamma counting analys... | Eur J Med Chem 145: 273-290 (2018) Article DOI: 10.1016/j.ejmech.2017.12.021 BindingDB Entry DOI: 10.7270/Q2639S81 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-1 angiotensin II receptor (Homo sapiens (Human)) | BDBM50049186 ((S)-3-Methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Darmstadt Curated by ChEMBL | Assay Description Inhibition constant against Angiotensin II receptor, type 1 was determined | J Med Chem 46: 2261-70 (2003) Article DOI: 10.1021/jm0204237 BindingDB Entry DOI: 10.7270/Q2154HSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Type-2 angiotensin II receptor (Homo sapiens (Human)) | BDBM50049186 ((S)-3-Methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-b...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance Biopharma US Inc. Curated by ChEMBL | Assay Description Displacement of Europium-labeled angiotensin-2 from human AT2 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIA | ACS Med Chem Lett 10: 86-91 (2019) Article DOI: 10.1021/acsmedchemlett.8b00462 BindingDB Entry DOI: 10.7270/Q2D50R6V | |||||||||||
More data for this Ligand-Target Pair |