Compile Data Set for Download or QSAR

Found 8 hits of kd for drug = Combivir   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Binding affinity to HIV1 reverse transcriptase assessed as L-3'-azido-NTP incorporation in nascent DNA				Eur J Med Chem 46: 3832-44 (2011) Article DOI: 10.1016/j.ejmech.2011.05.051 BindingDB Entry DOI: 10.7270/Q2RN3BQP
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Binding affinity to HIV1 reverse transcriptase				Antimicrob Agents Chemother 53: 3715-9 (2009) Article DOI: 10.1128/AAC.00392-09 BindingDB Entry DOI: 10.7270/Q2KD21R2
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Binding affinity to wild type HIV1 LAI reverse transcriptase				Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant				Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant				Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh School of Medicine Curated by ChEMBL					Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant				Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Equilibrium binding constant at the active site of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 14: 437-40 (2003) BindingDB Entry DOI: 10.7270/Q2RX9BGK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) Show SMILES Nc1ccn([C@@H]2CS[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O2)c(=O)n1 |r| Show InChI InChI=1S/C8H14N3O12P3S/c9-5-1-2-11(8(12)10-5)6-4-27-7(21-6)3-20-25(16,17)23-26(18,19)22-24(13,14)15/h1-2,6-7H,3-4H2,(H,16,17)(H,18,19)(H2,9,10,12)(H2,13,14,15)/t6-,7+/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Binding affinity to HIV1 reverse transcriptase M184V mutant assessed as L-3'-azido-NTP incorporation in nascent DNA				Eur J Med Chem 46: 3832-44 (2011) Article DOI: 10.1016/j.ejmech.2011.05.051 BindingDB Entry DOI: 10.7270/Q2RN3BQP
					More data for this Ligand-Target Pair