BindingDB PrimarySearch

Found 4 hits of ic50 for monomerid = 50138670
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138670 (6-Carbamimidoyl-naphthalene-2-carboxylic acid phen...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by spectrop...				Bioorg Med Chem 20: 1557-68 (2012) Article DOI: 10.1016/j.bmc.2011.12.040 BindingDB Entry DOI: 10.7270/Q2QR4XK1
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Plasminogen (Homo sapiens (Human))	BDBM50138670 (6-Carbamimidoyl-naphthalene-2-carboxylic acid phen...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human plasma plasmin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins ...				Bioorg Med Chem 20: 1557-68 (2012) Article DOI: 10.1016/j.bmc.2011.12.040 BindingDB Entry DOI: 10.7270/Q2QR4XK1
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50138670 (6-Carbamimidoyl-naphthalene-2-carboxylic acid phen...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of human plasma thrombin using pyroGlu-Pro-Arg-p-NA.HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins...				Bioorg Med Chem 20: 1557-68 (2012) Article DOI: 10.1016/j.bmc.2011.12.040 BindingDB Entry DOI: 10.7270/Q2QR4XK1
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50138670 (6-Carbamimidoyl-naphthalene-2-carboxylic acid phen...) Show SMILES NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp Curated by ChEMBL					Assay Description Inhibition of recombinant tPA using H-D-Ile-Pro-Arg-pNA.2HCl as substrate preincubated for 15 mins prior sustrate addition measured for 10 mins by sp...				Bioorg Med Chem 20: 1557-68 (2012) Article DOI: 10.1016/j.bmc.2011.12.040 BindingDB Entry DOI: 10.7270/Q2QR4XK1
University of Antwerp Curated by ChEMBL					More data for this Ligand-Target Pair