Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | n/a | 0.0650 | n/a | n/a | n/a | n/a | n/a |
Allergan Inc. Curated by ChEMBL | Assay Description Binding affinity to VDR receptor | J Med Chem 44: 281-97 (2001) BindingDB Entry DOI: 10.7270/Q2NP2541 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor A (Danio rerio) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
Institut de G£n£tique et de Biologie Mol£culaire et Cellulaire (IGBMC) Curated by ChEMBL | Assay Description Binding affinity to zebrafish VDR LBD assessed as Kd for fluorescein-labeled SRC1 NR2 peptide binding by micro-scale thermophoresis method | J Med Chem 63: 9457-9463 (2020) Article DOI: 10.1021/acs.jmedchem.0c00656 BindingDB Entry DOI: 10.7270/Q28919DP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Vitamin D-binding protein (Homo sapiens (Human)) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a |
Universidad de Oviedo Curated by ChEMBL | Assay Description Binding affinity to human vitamin D binding protein | J Med Chem 52: 6158-62 (2009) Article DOI: 10.1021/jm900711d BindingDB Entry DOI: 10.7270/Q2N87BRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Sus scrofa) | BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.0700 | n/a | n/a | n/a | n/a | n/a |
Universidad de Oviedo Curated by ChEMBL | Assay Description Displacement of [3H]1-alpha,25-(OH)2D3 from VDR in pig intestinal mucosa | J Med Chem 52: 6158-62 (2009) Article DOI: 10.1021/jm900711d BindingDB Entry DOI: 10.7270/Q2N87BRX | |||||||||||
More data for this Ligand-Target Pair |