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Compile Data Set for Download or QSAR

Found 4 hits of ic50 for UniProtKB: P10721   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mast/stem cell growth factor receptor Kit [V560G]


(Homo sapiens (Human))
BDBM504397
PNG
((S)-1-(4-fluorophenyl)-1-(2-(4-(6-(1-methyl-1H-pyr...)
Show SMILES Cn1cc(cn1)-c1cc2c(ccnn2c1)N1CCN(CC1)c1ncc(cn1)[C@@](C)(N)c1ccc(F)cc1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.5n/an/an/an/an/an/a


TBA

Assay Description
KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Q52SR0
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G]


(Homo sapiens (Human))
BDBM504400
PNG
((S)-4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrim...)
Show SMILES Cn1cc(cn1)-c1cc2c(N3CCN(CC3)c3ncc(cn3)[C@@](C)(N)c3ccc(F)cc3)c(cnn2c1)C#N |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.5n/an/an/an/an/an/a


TBA

Assay Description
KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Q52SR0
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G]


(Homo sapiens (Human))
BDBM504399
PNG
((S)-1-(2-(4-(3-chloro-6-(1-methyl-1H-pyrazol-4-yl)...)
Show SMILES Cn1cc(cn1)-c1cc2c(N3CCN(CC3)c3ncc(cn3)[C@@](C)(N)c3ccc(F)cc3)c(Cl)cnn2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a


TBA

Assay Description
KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Q52SR0
More data for this
Ligand-Target Pair
Mast/stem cell growth factor receptor Kit [V560G]


(Homo sapiens (Human))
BDBM504398
PNG
((S)-1-(2-(4-(3-fluoro-6-(1-methyl-11H-pyrazol-4-yl...)
Show SMILES Cn1cc(cn1)-c1cc2c(N3CCN(CC3)c3ncc(cn3)[C@@](C)(N)c3ccc(F)cc3)c(F)cnn2c1 |r|
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a


TBA

Assay Description
KIT, KIT mutant, and PDGFRα mutant kinase profiling was performed with recombinant enzymes including wild-type KIT, KIT V560G, KIT V559D/T670I, ...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2Q52SR0
More data for this
Ligand-Target Pair