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Compile Data Set for Download or QSAR

Found 1 hit of ec50 for UniProtKB: Q13510   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acid ceramidase


(Homo sapiens (Human))		BDBM50511298
PNG
(CHEMBL4451058)
Show SMILES CC(C)CNC(=O)n1c2ccc(cc2oc1=O)C1CCN(C)CC1
Show InChI InChI=1S/C18H25N3O3/c1-12(2)11-19-17(22)21-15-5-4-14(10-16(15)24-18(21)23)13-6-8-20(3)9-7-13/h4-5,10,12-13H,6-9,11H2,1-3H3,(H,19,22)
PDB

UniProtKB/SwissProt

antibodypedia
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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 410n/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of acid ceramidase in Krabbe's disease patient-derived primary fibroblasts using Rbm14-12 as substrate measured after 2 hrs by fluorescenc...

J Med Chem 63: 3634-3664 (2020)


Article DOI: 10.1021/acs.jmedchem.9b02004
BindingDB Entry DOI: 10.7270/Q20C503N
More data for this
Ligand-Target Pair