BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 17 hits of ec50 for UniProtKB: P27958   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243437
PNG
(US9427428, 18)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc2cc(ccc2c1)-c1cnc([nH]1)[C@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Show InChI InChI=1S/C43H50N8O7/c1-7-24(2)36(48-42(54)57-5)40(52)51-19-9-11-35(51)39-45-31-17-16-29(22-32(31)46-39)27-12-13-28-21-30(15-14-26(28)20-27)33-23-44-38(47-33)34-10-8-18-50(34)41(53)37(25(3)56-4)49-43(55)58-6/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27-,33-30+/t24-,25+,34+,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0180n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243439
PNG
(US9427428, 9 | US9433609, 9)
Show SMILES CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc2cc(ccc2c1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
Show InChI InChI=1S/C42H48N8O7/c1-23(2)35(47-41(53)56-5)39(51)49-17-7-9-33(49)37-43-22-32(46-37)29-14-13-25-19-26(11-12-27(25)20-29)28-15-16-30-31(21-28)45-38(44-30)34-10-8-18-50(34)40(52)36(24(3)55-4)48-42(54)57-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,47,53)(H,48,54)/b28-26-,32-29+/t24-,33+,34+,35+,36+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0300n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243435
PNG
(US9427428, 4)
Show SMILES CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Show InChI InChI=1S/C42H48N8O8/c1-23(55-3)35(47-41(53)57-5)39(51)49-17-7-9-33(49)37-43-22-32(46-37)29-14-13-25-19-26(11-12-27(25)20-29)28-15-16-30-31(21-28)45-38(44-30)34-10-8-18-50(34)40(52)36(24(2)56-4)48-42(54)58-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,47,53)(H,48,54)/b28-26-,32-29+/t23-,24-,33+,34+,35+,36+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0330n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243438
PNG
(US9427428, 11)
Show SMILES CO[C@H](C)[C@@H](NC(=O)OC)C(=O)N1CCC[C@@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@H](NC(=O)OC)C(C)C |r|
Show InChI InChI=1S/C42H48N8O7/c1-23(2)35(47-41(53)56-5)39(51)50-18-8-10-34(50)38-44-30-16-15-28(21-31(30)45-38)26-11-12-27-20-29(14-13-25(27)19-26)32-22-43-37(46-32)33-9-7-17-49(33)40(52)36(24(3)55-4)48-42(54)57-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,47,53)(H,48,54)/b28-26-,32-29+/t24-,33-,34+,35-,36-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0480n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243436
PNG
(US9427428, 17 | US9427428, 21)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Show InChI InChI=1S/C43H50N8O7/c1-7-24(2)36(48-42(54)57-5)40(52)50-18-8-10-34(50)38-44-23-33(47-38)30-15-14-26-20-27(12-13-28(26)21-30)29-16-17-31-32(22-29)46-39(45-31)35-11-9-19-51(35)41(53)37(25(3)56-4)49-43(55)58-6/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27-,33-30+/t24-,25+,34-,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0490n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243443
PNG
(US9427428, 3 | US9433609, 3)
Show SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
Show InChI InChI=1S/C42H48N8O6/c1-23(2)35(47-41(53)55-5)39(51)49-17-7-9-33(49)37-43-22-32(46-37)29-14-13-25-19-26(11-12-27(25)20-29)28-15-16-30-31(21-28)45-38(44-30)34-10-8-18-50(34)40(52)36(24(3)4)48-42(54)56-6/h11-16,19-24,33-36H,7-10,17-18H2,1-6H3,(H,47,53)(H,48,54)/b28-26+,32-29-/t33-,34-,35-,36-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0510n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243449
PNG
(US9427428, 13 | US9433609, 13)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc2cc(ccc2c1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
Show InChI InChI=1S/C43H50N8O6/c1-7-25(4)37(49-43(55)57-6)41(53)51-19-9-11-35(51)39-45-31-17-16-29(22-32(31)46-39)27-12-13-28-21-30(15-14-26(28)20-27)33-23-44-38(47-33)34-10-8-18-50(34)40(52)36(24(2)3)48-42(54)56-5/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27-,33-30+/t25-,34-,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0510n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243452
PNG
(US9427428, 16 | US9433609, 16)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2[nH]c(nc2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C |r|
Show InChI InChI=1S/C43H50N8O6/c1-7-25(4)37(49-43(55)57-6)41(53)50-18-8-10-34(50)38-44-23-33(47-38)30-15-14-26-20-27(12-13-28(26)21-30)29-16-17-31-32(22-29)46-39(45-31)35-11-9-19-51(35)40(52)36(24(2)3)48-42(54)56-5/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27+,33-30-/t25-,34-,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.0980n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243440
PNG
(US9427428, 6 | US9433609, 6)
Show SMILES COC(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)O |r|
Show InChI InChI=1S/C40H44N8O8/c1-21(49)33(45-39(53)55-3)37(51)47-15-5-7-31(47)35-41-20-30(44-35)27-12-11-23-17-24(9-10-25(23)18-27)26-13-14-28-29(19-26)43-36(42-28)32-8-6-16-48(32)38(52)34(22(2)50)46-40(54)56-4/h9-14,17-22,31-34,49-50H,5-8,15-16H2,1-4H3,(H,45,53)(H,46,54)/b26-24-,30-27+/t21-,22-,31+,32+,33+,34+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.181n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243446
PNG
(US9427428, 8 | US9433609, 8)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)CC |r|
Show InChI InChI=1S/C44H52N8O6/c1-7-25(3)37(49-43(55)57-5)41(53)51-19-9-11-35(51)39-45-24-34(48-39)31-16-15-27-21-28(13-14-29(27)22-31)30-17-18-32-33(23-30)47-40(46-32)36-12-10-20-52(36)42(54)38(26(4)8-2)50-44(56)58-6/h13-18,21-26,35-38H,7-12,19-20H2,1-6H3,(H,49,55)(H,50,56)/b30-28+,34-31-/t25-,26-,35-,36-,37-,38-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.204n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243448
PNG
(US9427428, 12 | US9433609, 12)
Show SMILES COC(=O)NC(C1CCOCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)C(NC(=O)OC)C1CCOCC1 |r|
Show InChI InChI=1S/C46H52N8O8/c1-59-45(57)51-39(27-13-19-61-20-14-27)43(55)53-17-3-5-37(53)41-47-26-36(50-41)33-10-9-29-23-30(7-8-31(29)24-33)32-11-12-34-35(25-32)49-42(48-34)38-6-4-18-54(38)44(56)40(52-46(58)60-2)28-15-21-62-22-16-28/h7-12,23-28,37-40H,3-6,13-22H2,1-2H3,(H,51,57)(H,52,58)/b32-30+,36-33-/t37-,38-,39?,40?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.268n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243451
PNG
(US9427428, 15 | US9433609, 15)
Show SMILES COC(=O)N[C@@H](C1CCCC1)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C1CCCC1 |r|
Show InChI InChI=1S/C46H52N8O6/c1-59-45(57)51-39(27-9-3-4-10-27)43(55)53-21-7-13-37(53)41-47-26-36(50-41)33-18-17-29-23-30(15-16-31(29)24-33)32-19-20-34-35(25-32)49-42(48-34)38-14-8-22-54(38)44(56)40(52-46(58)60-2)28-11-5-6-12-28/h15-20,23-28,37-40H,3-14,21-22H2,1-2H3,(H,51,57)(H,52,58)/b32-30+,36-33-/t37-,38-,39-,40-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.277n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243434
PNG
(US9427428, 19)
Show SMILES CC[C@@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)CC |r|
Show InChI InChI=1S/C44H52N8O6/c1-7-25(3)37(49-43(55)57-5)41(53)51-19-9-11-35(51)39-45-24-34(48-39)31-16-15-27-21-28(13-14-29(27)22-31)30-17-18-32-33(23-30)47-40(46-32)36-12-10-20-52(36)42(54)38(26(4)8-2)50-44(56)58-6/h13-18,21-26,35-38H,7-12,19-20H2,1-6H3,(H,49,55)(H,50,56)/b30-28-,34-31+/t25-,26+,35+,36+,37+,38+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.471n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243450
PNG
(US9427428, 14 | US9433609, 14)
Show SMILES COC(=O)NC(C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)C(NC(=O)OC)c1ccccc1)c1ccccc1 |r|
Show InChI InChI=1S/C48H44N8O6/c1-61-47(59)53-41(29-11-5-3-6-12-29)45(57)55-23-9-15-39(55)43-49-28-38(52-43)35-20-19-31-25-32(17-18-33(31)26-35)34-21-22-36-37(27-34)51-44(50-36)40-16-10-24-56(40)46(58)42(54-48(60)62-2)30-13-7-4-8-14-30/h3-8,11-14,17-22,25-28,39-42H,9-10,15-16,23-24H2,1-2H3,(H,53,59)(H,54,60)/b34-32+,38-35-/t39-,40-,41?,42?/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.836n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243445
PNG
(US9427428, 7 | US9433609, 7)
Show SMILES COC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)OC |r|
Show InChI InChI=1S/C44H52N8O6/c1-25(2)19-34(49-43(55)57-5)41(53)51-17-7-9-37(51)39-45-24-36(48-39)31-14-13-27-21-28(11-12-29(27)22-31)30-15-16-32-33(23-30)47-40(46-32)38-10-8-18-52(38)42(54)35(20-26(3)4)50-44(56)58-6/h11-16,21-26,34-35,37-38H,7-10,17-20H2,1-6H3,(H,49,55)(H,50,56)/b30-28+,36-31-/t34-,35-,37-,38-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.989n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243453
PNG
(US9427428, 20)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2ccc(cc2[nH]1)-c1ccc2cc(ccc2c1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Show InChI InChI=1S/C43H50N8O7/c1-7-24(2)36(48-42(54)57-5)40(52)51-19-9-11-35(51)39-45-31-17-16-29(22-32(31)46-39)27-12-13-28-21-30(15-14-26(28)20-27)33-23-44-38(47-33)34-10-8-18-50(34)41(53)37(25(3)56-4)49-43(55)58-6/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27-,33-30+/t24-,25+,34-,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 324n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair
Genome polyprotein [1027-3011]


(Hepatitis C virus genotype 1a (isolate H) (HCV))		BDBM243436
PNG
(US9427428, 17 | US9427428, 21)
Show SMILES CC[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC |r|
Show InChI InChI=1S/C43H50N8O7/c1-7-24(2)36(48-42(54)57-5)40(52)50-18-8-10-34(50)38-44-23-33(47-38)30-15-14-26-20-27(12-13-28(26)21-30)29-16-17-31-32(22-29)46-39(45-31)35-11-9-19-51(35)41(53)37(25(3)56-4)49-43(55)58-6/h12-17,20-25,34-37H,7-11,18-19H2,1-6H3,(H,48,54)(H,49,55)/b29-27-,33-30+/t24-,25+,34-,35-,36-,37-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 482n/an/an/an/a



Janssen Sciences Ireland UC

US Patent


Assay Description
In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...

US Patent US9427428 (2016)


BindingDB Entry DOI: 10.7270/Q2JD4VPJ
More data for this
Ligand-Target Pair