Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase I (Leishmania donovani) | BDBM50239186 (1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.30E+5 | n/a | n/a | n/a | n/a | n/a |
India Institute of Chemical Biology Curated by ChEMBL | Assay Description Binding affinity to recombinant drug-resistant Leishmania donovani LdDR50 topoisomerase 1b large subunit F270L mutant after 24 hrs by equilibrium dia... | Antimicrob Agents Chemother 53: 2589-98 (2009) Article DOI: 10.1128/AAC.01648-08 BindingDB Entry DOI: 10.7270/Q2542RDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase I (Leishmania donovani) | BDBM50239186 (1,1-Bis(3''-Indolyl)Methane | 3,3''-Diindolylmetha...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.60E+5 | n/a | n/a | n/a | n/a | n/a |
India Institute of Chemical Biology Curated by ChEMBL | Assay Description Binding affinity to recombinant drug-resistant Leishmania donovani LdDR50 topoisomerase 1b large subunit F270L, K430N mutant after 24 hrs by equilibr... | Antimicrob Agents Chemother 53: 2589-98 (2009) Article DOI: 10.1128/AAC.01648-08 BindingDB Entry DOI: 10.7270/Q2542RDS | |||||||||||
More data for this Ligand-Target Pair |