Found 58 hits of ic50 for UniProtKB: P01857 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM507127
(US11046675, Example 1006)Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)c3CN(CC(O)=O)CCc3c2Cl)cccc1-c1cccc(OCCCN2CC[C@@H](O)C2)c1C |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2377CVC |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581058
(US11492375, Example 1120)Show SMILES C[C@@H]1NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CCCCN3C(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CSC[C@H](NC1=O)C(=O)NCC(N)=O)C(=O)N2C |r,c:10| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM507051
(US11046675, Example 1001)Show SMILES Cc1c(COc2cc3CCN(CC(O)=O)Cc3c(OCc3cncc(c3)C#N)c2)cccc1-c1ccc2OCCOc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2377CVC |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581053
(US11492375, Example 1115)Show SMILES C[C@@H]1NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CNCCN3C(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CSC[C@H](NC1=O)C(=O)NCC(N)=O)C(=O)N2C |r,c:10| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM507128
(US11046675, Example 1007)Show SMILES COC(=O)c1cncc(COc2cc(OCc3cccc(c3C)-c3cccc(OCCCN4CC[C@@H](O)C4)c3C)c(Cl)c3CCN(CC(O)=O)Cc23)c1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2377CVC |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412139
(US10392405, Compound Id 1.003 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1F |r| Show InChI InChI=1S/C34H33ClFN3O5/c1-21-23(7-6-9-26(21)27-8-2-3-10-29(27)36)20-44-32-15-31-24(14-28(32)35)18-39-30(34(41)42)11-4-5-12-38-33(40)25-13-22(19-43-31)16-37-17-25/h2-3,6-10,13-17,30,39H,4-5,11-12,18-20H2,1H3,(H,38,40)(H,41,42)/t30-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412140
(US10392405, Compound Id 1.004 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1cccc(OCCCN2CCC(O)CC2)c1C |r| Show InChI InChI=1S/C43H51ClN4O7/c1-28-31(8-5-9-35(28)36-10-6-12-39(29(36)2)53-19-7-16-48-17-13-34(49)14-18-48)27-55-41-22-40-32(21-37(41)44)25-47-38(43(51)52)11-3-4-15-46-42(50)33-20-30(26-54-40)23-45-24-33/h5-6,8-10,12,20-24,34,38,47,49H,3-4,7,11,13-19,25-27H2,1-2H3,(H,46,50)(H,51,52)/t38-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581040
(US11492375, Example 1102)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CC\C=C/CC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:75| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412138
(US10392405, Compound Id 1.002 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccc2OCCOc2c1 |r| Show InChI InChI=1S/C36H36ClN3O7/c1-22-25(5-4-6-28(22)24-8-9-31-34(15-24)45-12-11-44-31)21-47-33-16-32-26(14-29(33)37)19-40-30(36(42)43)7-2-3-10-39-35(41)27-13-23(20-46-32)17-38-18-27/h4-6,8-9,13-18,30,40H,2-3,7,10-12,19-21H2,1H3,(H,39,41)(H,42,43)/t30-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412137
(US10392405, Compound Id 1.001 | US11059834, Compou...)Show SMILES COc1cccc(c1F)-c1cccc(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)c1C |r| Show InChI InChI=1S/C35H35ClFN3O6/c1-21-23(7-5-8-26(21)27-9-6-11-30(44-2)33(27)37)20-46-32-15-31-24(14-28(32)36)18-40-29(35(42)43)10-3-4-12-39-34(41)25-13-22(19-45-31)16-38-17-25/h5-9,11,13-17,29,40H,3-4,10,12,18-20H2,1-2H3,(H,39,41)(H,42,43)/t29-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581043
(US11492375, Example 1105)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2COCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](C)NC(=O)C2CCC\C=C/CCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:73| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581044
(US11492375, Example 1106)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](C)NC(=O)[C@H]2CCC\C=C/CCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:65| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412160
(US10392405, Compound Id 1.024 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@@H](CO)NCc3cc2Cl)cccc1-c1cccc(OCCCN2CC[C@@H](O)C2)c1C |r| Show InChI InChI=1S/C42H51ClN4O6/c1-28-31(8-5-10-36(28)37-11-6-12-39(29(37)2)51-17-7-15-47-16-13-35(49)24-47)27-53-41-20-40-32(19-38(41)43)23-46-34(25-48)9-3-4-14-45-42(50)33-18-30(26-52-40)21-44-22-33/h5-6,8,10-12,18-22,34-35,46,48-49H,3-4,7,9,13-17,23-27H2,1-2H3,(H,45,50)/t34-,35+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412158
(US10392405, Compound Id 1.022 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cc(cc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)C#N)cccc1-c1cccc(OCCCN2CCC(O)CC2)c1C |r| Show InChI InChI=1S/C45H51ClN4O7/c1-29-33(8-5-9-37(29)38-10-6-12-41(30(38)2)55-19-7-16-50-17-13-36(51)14-18-50)28-57-43-24-42-35(23-39(43)46)26-49-40(45(53)54)11-3-4-15-48-44(52)34-21-31(25-47)20-32(22-34)27-56-42/h5-6,8-10,12,20-24,36,40,49,51H,3-4,7,11,13-19,26-28H2,1-2H3,(H,48,52)(H,53,54)/t40-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412159
(US10392405, Compound Id 1.023 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cc(cc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)C#N)cccc1-c1cccc(OCCCN2CC[C@@H](O)C2)c1C |r| Show InChI InChI=1S/C44H49ClN4O7/c1-28-32(8-5-9-36(28)37-10-6-12-40(29(37)2)54-17-7-15-49-16-13-35(50)25-49)27-56-42-22-41-34(21-38(42)45)24-48-39(44(52)53)11-3-4-14-47-43(51)33-19-30(23-46)18-31(20-33)26-55-41/h5-6,8-10,12,18-22,35,39,48,50H,3-4,7,11,13-17,24-27H2,1-2H3,(H,47,51)(H,52,53)/t35-,39+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412157
(US10392405, Compound Id 1.021 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cc(cc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)C#N)cccc1-c1cccc(OCCCN2CCC(F)CC2)c1C |r| Show InChI InChI=1S/C45H50ClFN4O6/c1-29-33(8-5-9-37(29)38-10-6-12-41(30(38)2)55-19-7-16-51-17-13-36(47)14-18-51)28-57-43-24-42-35(23-39(43)46)26-50-40(45(53)54)11-3-4-15-49-44(52)34-21-31(25-48)20-32(22-34)27-56-42/h5-6,8-10,12,20-24,36,40,50H,3-4,7,11,13-19,26-28H2,1-2H3,(H,49,52)(H,53,54)/t40-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412156
(US10392405, Compound Id 1.020 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1cccc(OCCCN2CC(O)C2)c1C |r| Show InChI InChI=1S/C41H47ClN4O7/c1-26-29(8-5-9-33(26)34-10-6-12-37(27(34)2)51-15-7-14-46-22-32(47)23-46)25-53-39-18-38-30(17-35(39)42)21-45-36(41(49)50)11-3-4-13-44-40(48)31-16-28(24-52-38)19-43-20-31/h5-6,8-10,12,16-20,32,36,45,47H,3-4,7,11,13-15,21-25H2,1-2H3,(H,44,48)(H,49,50)/t36-/m0/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412155
(US10392405, Compound Id 1.019 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1cccc(OCCCN2CCC(O)CC2)c1C |r| Show InChI InChI=1S/C45H55ClN4O7/c1-30-33(10-7-11-37(30)38-12-8-14-41(31(38)2)55-21-9-18-50-19-15-36(51)16-20-50)29-57-43-24-42-34(23-39(43)46)27-49-40(45(53)54)13-5-3-4-6-17-48-44(52)35-22-32(28-56-42)25-47-26-35/h7-8,10-12,14,22-26,36,40,49,51H,3-6,9,13,15-21,27-29H2,1-2H3,(H,48,52)(H,53,54)/t40-/m0/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412154
(US10392405, Compound Id 1.018 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1cccc(OCCCN2CC[C@@H](O)C2)c1C |r| Show InChI InChI=1S/C42H49ClN4O7/c1-27-30(8-5-9-34(27)35-10-6-12-38(28(35)2)52-17-7-15-47-16-13-33(48)24-47)26-54-40-20-39-31(19-36(40)43)23-46-37(42(50)51)11-3-4-14-45-41(49)32-18-29(25-53-39)21-44-22-32/h5-6,8-10,12,18-22,33,37,46,48H,3-4,7,11,13-17,23-26H2,1-2H3,(H,45,49)(H,50,51)/t33-,37+/m1/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581039
(US11492375, Example 1101)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCC\C=C/CCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:76| | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412161
(US10392405, Compound Id 1.025 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@@H](CO)NCc3cc2Cl)cccc1-c1cccc(OCCCN2CCC(F)CC2)c1C |r| Show InChI InChI=1S/C43H52ClFN4O5/c1-29-32(8-5-10-37(29)38-11-6-12-40(30(38)2)52-19-7-16-49-17-13-35(45)14-18-49)28-54-42-22-41-33(21-39(42)44)25-48-36(26-50)9-3-4-15-47-43(51)34-20-31(27-53-41)23-46-24-34/h5-6,8,10-12,20-24,35-36,48,50H,3-4,7,9,13-19,25-28H2,1-2H3,(H,47,51)/t36-/m0/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412150
(US10392405, Compound Id 1.014 | US11059834, Compou...)Show SMILES OC(=O)[C@@H]1CCCCNC(=O)c2cncc(COc3cc(O[C@H]4CCc5c4cccc5-c4ccc5OCCOc5c4F)c(Cl)cc3CN1)c2 |r| Show InChI InChI=1S/C37H35ClFN3O7/c38-28-15-22-19-42-29(37(44)45)6-1-2-11-41-36(43)23-14-21(17-40-18-23)20-48-32(22)16-33(28)49-30-9-7-25-24(4-3-5-26(25)30)27-8-10-31-35(34(27)39)47-13-12-46-31/h3-5,8,10,14-18,29-30,42H,1-2,6-7,9,11-13,19-20H2,(H,41,43)(H,44,45)/t29-,30-/m0/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412151
(US10392405, Compound Id 1.015 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C34H34ClN3O5/c1-22-25(10-7-11-28(22)24-8-3-2-4-9-24)21-43-32-16-31-26(15-29(32)35)19-38-30(34(40)41)12-5-6-13-37-33(39)27-14-23(20-42-31)17-36-18-27/h2-4,7-11,14-18,30,38H,5-6,12-13,19-21H2,1H3,(H,37,39)(H,40,41)/t30-/m1/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412152
(US10392405, Compound Id 1.016 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C34H34ClN3O5/c1-22-25(10-7-11-28(22)24-8-3-2-4-9-24)21-43-32-16-31-26(15-29(32)35)19-38-30(34(40)41)12-5-6-13-37-33(39)27-14-23(20-42-31)17-36-18-27/h2-4,7-11,14-18,30,38H,5-6,12-13,19-21H2,1H3,(H,37,39)(H,40,41)/t30-/m0/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412140
(US10392405, Compound Id 1.004 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1cccc(OCCCN2CCC(O)CC2)c1C |r| Show InChI InChI=1S/C43H51ClN4O7/c1-28-31(8-5-9-35(28)36-10-6-12-39(29(36)2)53-19-7-16-48-17-13-34(49)14-18-48)27-55-41-22-40-32(21-37(41)44)25-47-38(43(51)52)11-3-4-15-46-42(50)33-20-30(26-54-40)23-45-24-33/h5-6,8-10,12,20-24,34,38,47,49H,3-4,7,11,13-19,25-27H2,1-2H3,(H,46,50)(H,51,52)/t38-/m0/s1 | PDB
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| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412147
(US10392405, Compound Id 1.011 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCCC[C@@H](CC(O)=O)NCc3cc2Cl)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C35H36ClN3O5/c1-23-26(10-7-12-30(23)25-8-3-2-4-9-25)22-44-33-17-32-27(15-31(33)36)20-39-29(16-34(40)41)11-5-6-13-38-35(42)28-14-24(21-43-32)18-37-19-28/h2-4,7-10,12,14-15,17-19,29,39H,5-6,11,13,16,20-22H2,1H3,(H,38,42)(H,40,41)/t29-/m0/s1 | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412146
(US10392405, Compound Id 1.010 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C33H32ClN3O5/c1-21-24(9-5-10-27(21)23-7-3-2-4-8-23)20-42-31-15-30-25(14-28(31)34)18-37-29(33(39)40)11-6-12-36-32(38)26-13-22(19-41-30)16-35-17-26/h2-5,7-10,13-17,29,37H,6,11-12,18-20H2,1H3,(H,36,38)(H,39,40)/t29-/m0/s1 | PDB
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TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412148
(US10392405, Compound Id 1.012 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCCCCC(=O)NCCCC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C32H37ClN2O5/c1-22-24(12-9-13-26(22)23-10-3-2-4-11-23)21-40-30-19-29-25(18-27(30)33)20-35-28(32(37)38)14-5-7-16-34-31(36)15-6-8-17-39-29/h2-4,9-13,18-19,28,35H,5-8,14-17,20-21H2,1H3,(H,34,36)(H,37,38)/t28-/m0/s1 | PDB
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TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412144
(US10392405, Compound Id 1.008 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCOC[C@H](NCc3cc2Cl)C(O)=O)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C33H32ClN3O6/c1-21-24(8-5-9-27(21)23-6-3-2-4-7-23)19-43-31-14-30-25(13-28(31)34)17-37-29(33(39)40)20-41-11-10-36-32(38)26-12-22(18-42-30)15-35-16-26/h2-9,12-16,29,37H,10-11,17-20H2,1H3,(H,36,38)(H,39,40)/t29-/m0/s1 | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412143
(US10392405, Compound Id 1.007 | US11059834, Compou...)Show SMILES OC(=O)[C@@H]1CCCCNC(=O)c2cncc(COc3cc(O[C@H]4CCc5c4cccc5-c4ccccc4F)c(Cl)cc3CN1)c2 |r| Show InChI InChI=1S/C35H33ClFN3O5/c36-28-15-22-19-40-30(35(42)43)10-3-4-13-39-34(41)23-14-21(17-38-18-23)20-44-32(22)16-33(28)45-31-12-11-25-24(7-5-8-27(25)31)26-6-1-2-9-29(26)37/h1-2,5-9,14-18,30-31,40H,3-4,10-13,19-20H2,(H,39,41)(H,42,43)/t30-,31-/m0/s1 | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM412142
(US10392405, Compound Id 1.006 | US11059834, Compou...)Show SMILES Cc1c(COc2cc3OCc4cncc(c4)C(=O)NCCNC(=O)[C@H](CO)NCc3cc2Cl)cccc1-c1ccccc1 |r| Show InChI InChI=1S/C33H33ClN4O5/c1-21-24(8-5-9-27(21)23-6-3-2-4-7-23)20-43-31-14-30-25(13-28(31)34)17-38-29(18-39)33(41)37-11-10-36-32(40)26-12-22(19-42-30)15-35-16-26/h2-9,12-16,29,38-39H,10-11,17-20H2,1H3,(H,36,40)(H,37,41)/t29-/m0/s1 | PDB
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| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2F192VF |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM507124
(US11046675, Example 1003)Show SMILES Cc1c(COc2cc(O)c3CN(CC(O)=O)CCc3c2)cccc1-c1ccc2OCCOc2c1 | PDB
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 775 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2377CVC |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM507123
(US11046675, Example 1002)Show SMILES Cc1c(COc2cc(OCc3cncc(c3)C#N)cc3CCN(CC(O)=O)Cc23)cccc1-c1ccc2OCCOc2c1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 775 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2377CVC |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581031
(US11492375, Example 1001)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCC\C=C\CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)CN(C)C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,t:76| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581032
(US11492375, Example 1002)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCCC\C=C\CCCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)CN(C)C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,t:77| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581059
(US11492375, Example 1121)Show SMILES CN1[C@H]2CCCC=CCOc3ccc(C[C@H](N(C)C2=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CSCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCCC[C@@H]2C(=O)N[C@@H](CC(O)=O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@@H](Cc2c[nH]c4ccccc24)C(=O)N[C@@H](CCN)C(=O)N[C@@H](Cc2cn(CC(O)=O)c4ccccc24)C1=O)C(=O)NCC(N)=O)cc3 |r| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581054
(US11492375, Example 1116)Show SMILES C[C@@H]1N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCC\C=C/CCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:40| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581048
(US11492375, Example 1110)Show SMILES CC[C@@H](NC(=O)[C@@H](C)NC(=O)[C@@H]1CCC\C=C/CCC[C@H](N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2COCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CS)C(=O)N1C)C(=O)NCC(N)=O |r,c:15| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581045
(US11492375, Example 1107)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(N)=O |r,c:72| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581042
(US11492375, Example 1104)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](CCCN)NC(=O)[C@H]2CCC\C=C/CCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:68| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581038
(US11492375, Example 1100)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccccc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)CN(C)C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:76| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581041
(US11492375, Example 1103)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](C)NC(=O)[C@H]2CC\C=C/CC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:64| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581056
(US11492375, Example 1118)Show SMILES C[C@@H]1N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CN)NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3csc4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:37| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581060
(US11492375, Example 1122)Show SMILES C[C@@H]1N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCC\C=C/CCCCCC(N(C)C(=O)[C@H](Cc3cn(CC(O)=O)c4ccccc34)NC(=O)[C@H](CCN)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:40| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581055
(US11492375, Example 1117)Show SMILES C[C@@H]1N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3cn(CC(O)=O)c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:40| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581051
(US11492375, Example 1113 | US11492375, Example 111...)Show SMILES C[C@@H]1NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CSC[C@H](NC1=O)C(=O)NCC(N)=O)C(=O)N2C |r,c:10| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581051
(US11492375, Example 1113 | US11492375, Example 111...)Show SMILES C[C@@H]1NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CSC[C@H](NC1=O)C(=O)NCC(N)=O)C(=O)N2C |r,c:10| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581050
(US11492375, Example 1112)Show SMILES C[C@@H]1NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc3ccc(O)cc3)NC(=O)CSC[C@H](NC1=O)C(=O)NCC(N)=O)C(=O)N2C |r,c:10| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581046
(US11492375, Example 1108)Show SMILES C[C@@H]1N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CN)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(O)=O)NC1=O)C(=O)N2C)C(N)=O |r,c:40| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1 [25-167,N33K], Immunoglobulin heavy constant gamma 1 [99-330,C104S,C109S,C112S,L118I,P121S]/Programmed cell death 1 ligand 1 [18-239,H172E]
(Homo sapiens (Human)) | BDBM581047
(US11492375, Example 1109)Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](CN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N(C)C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H]2CCCC\C=C/CCCC[C@H](N(C)C(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](CO)NC(=O)[C@@H](Cc3c[nH]c4ccccc34)NC(=O)[C@@H]3C[C@@H](O)CN3C1=O)C(=O)N2C)C(=O)NCC(N)=O |r,c:72| | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The ability of the macrocyclic peptides of the present disclosure to bind to PD-L1 was investigated using a PD-1/PD-L1 Homogenous Time-Resolved Fluor... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6GQ7 |
More data for this
Ligand-Target Pair | |
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