Compile Data Set for Download or QSAR

Found 16 hits of ec50 for UniProtKB: P15170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526006 (3-(5-(((1S,2S)-2- (benzylamino)cyclohexyl)amino)-1...) Show SMILES O=C1N(Cc2cc(N[C@H]3CCCC[C@@H]3NCc3ccccc3)ccc12)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM525983 (3-(5-(methyl((1R,2R)-2- (methylamino)cyclohexyl)am...) Show SMILES CN[C@@H]1CCCC[C@H]1N(C)c1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM525977 (3-(5-(((1S,2S)-2- hydroxycyclohexyl)amino)-1- oxoi...) Show SMILES O[C@H]1CCCC[C@@H]1Nc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526020 (3-(5-(((1S,2S)-2-(benzyloxy) cyclohexyl)amino)- 1-...) Show SMILES O=C1N(Cc2cc(N[C@H]3CCCC[C@@H]3OCc3ccccc3)ccc12)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526271 (2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...) Show SMILES CN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526272 (5-(((1S,2S)-2-aminocyclohexyl) (methyl)amino)- 2-(...) Show SMILES CN([C@H]1CCCC[C@@H]1N)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526273 (2-(2,6-dioxopiperidin-3-yl)-5-(((1S,2S)-2- (ethyla...) Show SMILES CCN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526274 (2-(2,6-dioxopiperidin-3- yl)-5-(methyl((1S,2S)-2- ...) Show SMILES CN[C@H]1CCCCC[C@@H]1N(C)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526270 (US11185537, Compound Mix) Show SMILES OC=O.CN[C@H]1CC=CC[C@@H]1N(C)c1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r,c:6| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526280 (3-(5-(((1S,2S)-2- (methylamino)cyclohexyl)amino)-1...) Show SMILES CN[C@H]1CCCC[C@@H]1Nc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526281 (5-(((1S,2S)-2- (dimethylamino)cyclohexyl) (methyl)...) Show SMILES CN(C)[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526282 (5-(((1S,2S)-2- (dimethylamino)cyclohexyl)amino)-2-...) Show SMILES CN(C)[C@H]1CCCC[C@@H]1Nc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526265 (3-(5-(((1S,2S)-2- (isopropylamino)cyclohexyl)amino...) Show SMILES CC(C)N[C@H]1CCCC[C@@H]1Nc1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526078 (US11185537, Compound I-8 | US11185537, Compound I-...) Show SMILES CN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526078 (US11185537, Compound I-8 | US11185537, Compound I-...) Show SMILES CN[C@H]1CCCC[C@@H]1N(C)c1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Human)	BDBM526270 (US11185537, Compound Mix) Show SMILES OC=O.CN[C@H]1CC=CC[C@@H]1N(C)c1ccc2C(=O)N(Cc2c1)C1CCC(=O)NC1=O |r,c:6| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description The Prolabel system from DiscoverX was used to develop high-throughput and quantitative assays to measure changes in IKZF1, IKZF2, and GSPT1 protein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FX7DMN
					More data for this Ligand-Target Pair