Found 24 hits of ic50 for UniProtKB: P00956 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50524451
(CHEMBL4553017)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)CC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C17H27N7O6S/c1-3-8(2)10(18)16(27)23-31(28,29)5-4-9-12(25)13(26)17(30-9)24-7-22-11-14(19)20-6-21-15(11)24/h6-10,12-13,17,25-26H,3-5,18H2,1-2H3,(H,23,27)(H2,19,20,21)/t8-,9+,10-,12+,13+,17+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
KU Leuven
Curated by ChEMBL
| Assay Description
Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in... |
Eur J Med Chem 174: 252-264 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.045
BindingDB Entry DOI: 10.7270/Q26M3B73 |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227798
(CHEMBL42269)Show SMILES [Na+].[H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/p-1/b16-13+/t17-,18-,19?,20-,21-,24+,25-,26-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50366869
(CHEMBL603510)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C16H25N7O7S/c1-3-7(2)9(17)15(26)22-31(27,28)29-4-8-11(24)12(25)16(30-8)23-6-21-10-13(18)19-5-20-14(10)23/h5-9,11-12,16,24-25H,3-4,17H2,1-2H3,(H,22,26)(H2,18,19,20)/t7-,8+,9-,11+,12+,16?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 265 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibitory concentration against Escherichia coli Ile-tRNA synthetase |
Bioorg Med Chem Lett 15: 3389-93 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.035
BindingDB Entry DOI: 10.7270/Q28G8MGP |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227812
(CHEMBL288953)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\C(=O)c2ccccc2)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C23H32O6/c1-13(9-18(25)16-7-5-4-6-8-16)10-19-22(27)21(26)17(12-28-19)11-20-23(29-20)14(2)15(3)24/h4-9,14-15,17,19-24,26-27H,10-12H2,1-3H3/b13-9+/t14-,15-,17?,19-,20-,21+,22-,23-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 494 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227796
(CHEMBL38412)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(=O)OC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C27H46O9/c1-17(14-24(30)34-12-10-8-6-5-7-9-11-23(29)33-4)13-21-26(32)25(31)20(16-35-21)15-22-27(36-22)18(2)19(3)28/h14,18-22,25-28,31-32H,5-13,15-16H2,1-4H3/b17-14+/t18-,19-,20?,21-,22-,25+,26-,27-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227800
(CHEMBL40757)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\COCCCCCCCCC(=O)OC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C27H48O8/c1-18(12-14-33-13-10-8-6-5-7-9-11-24(29)32-4)15-22-26(31)25(30)21(17-34-22)16-23-27(35-23)19(2)20(3)28/h12,19-23,25-28,30-31H,5-11,13-17H2,1-4H3/b18-12+/t19-,20-,21?,22-,23-,25+,26-,27-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227811
(CHEMBL287840)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\C(=O)CCCCCCCCCC(=O)OC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C28H48O8/c1-18(14-22(30)12-10-8-6-5-7-9-11-13-25(31)34-4)15-23-27(33)26(32)21(17-35-23)16-24-28(36-24)19(2)20(3)29/h14,19-21,23-24,26-29,32-33H,5-13,15-17H2,1-4H3/b18-14+/t19-,20-,21?,23-,24-,26+,27-,28-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227797
(CHEMBL42195)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\SCCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C20H36O5S/c1-5-6-7-26-11-12(2)8-16-19(23)18(22)15(10-24-16)9-17-20(25-17)13(3)14(4)21/h11,13-23H,5-10H2,1-4H3/b12-11+/t13-,14-,15?,16-,17-,18+,19-,20-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50168733
((1S,2S)-1-[(2R,5R)-5-(6-Amino-purin-9-yl)-tetrahyd...)Show SMILES CC[C@H](C)[C@H]([NH3+])C(=O)NS(=O)(=O)O[C@@H]1CC[C@@H](O1)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C15H23N7O5S/c1-3-8(2)11(16)15(23)21-28(24,25)27-10-5-4-9(26-10)22-7-20-12-13(17)18-6-19-14(12)22/h6-11H,3-5,16H2,1-2H3,(H,21,23)(H2,17,18,19)/p+1/t8-,9+,10+,11-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibitory concentration against Escherichia coli Ile-tRNA synthetase |
Bioorg Med Chem Lett 15: 3389-93 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.035
BindingDB Entry DOI: 10.7270/Q28G8MGP |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227810
(CHEMBL2115370)Show SMILES [H][C@]1(O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\Sc2ccccc2)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C22H32O5S/c1-13(12-28-17-7-5-4-6-8-17)9-18-21(25)20(24)16(11-26-18)10-19-22(27-19)14(2)15(3)23/h4-8,12,14-16,18-25H,9-11H2,1-3H3/b13-12+/t14-,15-,16-,18-,19-,20+,21-,22-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227803
(CHEMBL40920)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\C(=O)CCCCCCCCCC(SC)(SC)SC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C30H54O6S3/c1-20(16-24(32)14-12-10-8-7-9-11-13-15-30(37-4,38-5)39-6)17-25-28(34)27(33)23(19-35-25)18-26-29(36-26)21(2)22(3)31/h16,21-23,25-29,31,33-34H,7-15,17-19H2,1-6H3/b20-16+/t21-,22-,23?,25-,26-,27+,28-,29-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227808
(CHEMBL41447)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\CSCCCCCCCCC(=O)OC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C27H48O7S/c1-18(12-14-35-13-10-8-6-5-7-9-11-24(29)32-4)15-22-26(31)25(30)21(17-33-22)16-23-27(34-23)19(2)20(3)28/h12,19-23,25-28,30-31H,5-11,13-17H2,1-4H3/b18-12+/t19-,20-,21?,22-,23-,25+,26-,27-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50370456
(CHEMBL1789970)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)O[C@@H]1C[C@@H](O)[C@@H](O1)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C15H23N7O6S/c1-3-7(2)10(16)14(24)21-29(25,26)28-9-4-8(23)15(27-9)22-6-20-11-12(17)18-5-19-13(11)22/h5-10,15,23H,3-4,16H2,1-2H3,(H,21,24)(H2,17,18,19)/t7-,8+,9+,10-,15+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibitory concentration against Escherichia coli Ile-tRNA synthetase |
Bioorg Med Chem Lett 15: 3389-93 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.035
BindingDB Entry DOI: 10.7270/Q28G8MGP |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227795
(CHEMBL2114438)Show SMILES [H][C@]1(O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C/Sc2ccccc2)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C22H32O5S/c1-13(12-28-17-7-5-4-6-8-17)9-18-21(25)20(24)16(11-26-18)10-19-22(27-19)14(2)15(3)23/h4-8,12,14-16,18-25H,9-11H2,1-3H3/b13-12-/t14-,15-,16-,18-,19-,20+,21-,22-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227807
(CHEMBL431719)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\COCCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C21H38O6/c1-5-6-8-25-9-7-13(2)10-17-20(24)19(23)16(12-26-17)11-18-21(27-18)14(3)15(4)22/h7,14-24H,5-6,8-12H2,1-4H3/b13-7+/t14-,15-,16?,17-,18-,19+,20-,21-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 5.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227801
(CHEMBL290861)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\[S+]([O-])CCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C20H36O6S/c1-5-6-7-27(24)11-12(2)8-16-19(23)18(22)15(10-25-16)9-17-20(26-17)13(3)14(4)21/h11,13-23H,5-10H2,1-4H3/b12-11+/t13-,14-,15?,16-,17-,18+,19-,20-,27?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227802
(CHEMBL412877)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\S(=O)(=O)CCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C20H36O7S/c1-5-6-7-28(24,25)11-12(2)8-16-19(23)18(22)15(10-26-16)9-17-20(27-17)13(3)14(4)21/h11,13-23H,5-10H2,1-4H3/b12-11+/t13-,14-,15?,16-,17-,18+,19-,20-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50370457
(CHEMBL1789972)Show SMILES CC[C@H](C)[C@H](N)C(=O)NS(=O)(=O)O[C@H]1O[C@H](C[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C15H23N7O6S/c1-3-7(2)10(16)14(24)21-29(25,26)28-15-8(23)4-9(27-15)22-6-20-11-12(17)18-5-19-13(11)22/h5-10,15,23H,3-4,16H2,1-2H3,(H,21,24)(H2,17,18,19)/t7-,8-,9+,10-,15+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Inhibitory concentration against Escherichia coli Ile-tRNA synthetase |
Bioorg Med Chem Lett 15: 3389-93 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.035
BindingDB Entry DOI: 10.7270/Q28G8MGP |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227799
(CHEMBL41921)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\CSCCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C21H38O5S/c1-5-6-8-27-9-7-13(2)10-17-20(24)19(23)16(12-25-17)11-18-21(26-18)14(3)15(4)22/h7,14-24H,5-6,8-12H2,1-4H3/b13-7+/t14-,15-,16?,17-,18-,19+,20-,21-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 3.89E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227804
(CHEMBL44562)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C/SCCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C20H36O5S/c1-5-6-7-26-11-12(2)8-16-19(23)18(22)15(10-24-16)9-17-20(25-17)13(3)14(4)21/h11,13-23H,5-10H2,1-4H3/b12-11-/t13-,14-,15?,16-,17-,18+,19-,20-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 7.43E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227805
(CHEMBL415885)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](CC(=O)CC(=O)OCCCCCCCCC(=O)OC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C26H44O10/c1-16(17(2)27)26-21(36-26)12-18-15-35-20(25(32)24(18)31)13-19(28)14-23(30)34-11-9-7-5-4-6-8-10-22(29)33-3/h16-18,20-21,24-27,31-32H,4-15H2,1-3H3/t16-,17-,18?,20-,21-,24+,25-,26-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >7.74E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227806
(CHEMBL40737)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](CC2=CC(=O)OC2)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O |t:11| Show InChI InChI=1S/C17H26O7/c1-8(9(2)18)17-13(24-17)5-11-7-22-12(16(21)15(11)20)3-10-4-14(19)23-6-10/h4,8-9,11-13,15-18,20-21H,3,5-7H2,1-2H3/t8-,9-,11?,12-,13-,15+,16-,17-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 7.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227801
(CHEMBL290861)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](C\C(C)=C\[S+]([O-])CCCC)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C20H36O6S/c1-5-6-7-27(24)11-12(2)8-16-19(23)18(22)15(10-25-16)9-17-20(26-17)13(3)14(4)21/h11,13-23H,5-10H2,1-4H3/b12-11+/t13-,14-,15?,16-,17-,18+,19-,20-,27?/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | >9.88E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Isoleucine--tRNA ligase
(Escherichia coli) | BDBM50227809
(CHEMBL41562)Show SMILES [H][C@]1(O[C@H]1CC1CO[C@@H](Cc2ccoc2)[C@H](O)[C@@H]1O)[C@@H](C)[C@H](C)O Show InChI InChI=1S/C17H26O6/c1-9(10(2)18)17-14(23-17)6-12-8-22-13(16(20)15(12)19)5-11-3-4-21-7-11/h3-4,7,9-10,12-20H,5-6,8H2,1-2H3/t9-,10-,12?,13-,14-,15+,16-,17-/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.22E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibitory activity against Isoleucyl-tRNA synthetase |
J Med Chem 32: 151-60 (1989)
BindingDB Entry DOI: 10.7270/Q28054TD |
More data for this
Ligand-Target Pair | |
Search and Browse
