Compile Data Set for Download or QSAR

Found 4 hits of ec50 for UniProtKB: Q9BY41   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM25150 ((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...) Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1 Show InChI InChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	216	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113213 BindingDB Entry DOI: 10.7270/Q26Q2260
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Histone deacetylase 8 (Homo sapiens (Human))	BDBM32203 (8-quinolinol | CHEMBL310555 | US10005735, Table 1....) Show SMILES Oc1cccc2cccnc12 Show InChI InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Substrate-dependent activation of HDAC8 (unknown origin) using FLUOR DE LYS as substrate incubated for 30 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115607 BindingDB Entry DOI: 10.7270/Q2W3811M
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50239391 (2-Mercapto-Benzoic Acid | CHEBI:59124 | THIOSALICY...) Show SMILES OC(=O)c1ccccc1S Show InChI InChI=1S/C7H6O2S/c8-7(9)5-3-1-2-4-6(5)10/h1-4,10H,(H,8,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Substrate-dependent activation of HDAC8 (unknown origin) using FLUOR DE LYS as substrate incubated for 30 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmc.2020.115607 BindingDB Entry DOI: 10.7270/Q2W3811M
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50465051 (CHEMBL4285950) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(CONC(=O)\C=C\c2cccc(c2)S(=O)(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C28H31BN2O6S/c1-27(2)28(3,4)37-29(36-27)23-16-13-22(14-17-23)20-35-30-26(32)18-15-21-9-8-12-25(19-21)38(33,34)31-24-10-6-5-7-11-24/h5-19,31H,20H2,1-4H3,(H,30,32)/b18-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.41E+5	n/a	n/a	n/a	n/a
Xavier University of Louisiana Curated by ChEMBL					Assay Description Inhibition of human HDAC8 using RHK(Ac)K(Ac)AMC as substrate				ACS Med Chem Lett 9: 149-154 (2018) Article DOI: 10.1021/acsmedchemlett.7b00504 BindingDB Entry DOI: 10.7270/Q2S75K03
					More data for this Ligand-Target Pair