Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity nerve growth factor receptor [440-796] (Homo sapiens (Human)) | BDBM27890 (8-(2,3-dihydro-1H-inden-5-yl)-2-({4-[2-(4-methylpi...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description TrkA was assayed using a fluorescence polarization (FP) competition immunoassay that measured TrkA phosphorylation of polyGlu4Tyr. The reaction was i... | J Med Chem 52: 1081-99 (2009) Article DOI: 10.1021/jm801406h BindingDB Entry DOI: 10.7270/Q21834T7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor [440-796] (Homo sapiens (Human)) | BDBM27908 (2-[4-(4-{[8-(2,3-dihydro-1H-inden-5-yl)-6-(methoxy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description TrkA was assayed using a fluorescence polarization (FP) competition immunoassay that measured TrkA phosphorylation of polyGlu4Tyr. The reaction was i... | J Med Chem 52: 1081-99 (2009) Article DOI: 10.1021/jm801406h BindingDB Entry DOI: 10.7270/Q21834T7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor [440-796] (Homo sapiens (Human)) | BDBM27909 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-{[4-(1-m...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description TrkA was assayed using a fluorescence polarization (FP) competition immunoassay that measured TrkA phosphorylation of polyGlu4Tyr. The reaction was i... | J Med Chem 52: 1081-99 (2009) Article DOI: 10.1021/jm801406h BindingDB Entry DOI: 10.7270/Q21834T7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
High affinity nerve growth factor receptor [440-796] (Homo sapiens (Human)) | BDBM27895 (8-(2,3-dihydro-1H-inden-5-yl)-N-methoxy-2-({4-[2-(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | 25 |
Johnson & Johnson Pharmaceutical | Assay Description TrkA was assayed using a fluorescence polarization (FP) competition immunoassay that measured TrkA phosphorylation of polyGlu4Tyr. The reaction was i... | J Med Chem 52: 1081-99 (2009) Article DOI: 10.1021/jm801406h BindingDB Entry DOI: 10.7270/Q21834T7 | |||||||||||
More data for this Ligand-Target Pair |