Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Replicase polyprotein 1ab [1541-1855] (Human SARS coronavirus (SARS-CoV)) | BDBM154573 (8-(trifluoromethyl)-9H-purin-6-amine (4) | acs.jme...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 1.15E+4 | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Illinois at Chicago | Assay Description done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff... | ACS Chem Biol 10: 1456-65 (2015) Article DOI: 10.1021/cb500917m BindingDB Entry DOI: 10.7270/Q2086426 | |||||||||||
More data for this Ligand-Target Pair |