Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380456 (US9926306, ID 183-82 | US9926306, ID 187-79) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380458 (US9926306, ID 183-88) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.16 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380459 (US9926306, ID 187-22) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.41 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380460 (US9926306, ID 183-8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380461 (US9926306, ID 187-20) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.78 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380462 (US9926306, ID 183-70) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.97 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380463 (US9926306, ID 178-82) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380464 (US9926306, ID 183-22) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380465 (US9926306, ID 187-5) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380466 (US9926306, ID 183-51) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380467 (US9926306, ID 183-19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380469 (US9926306, ID 187-27) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380468 (US9926306, ID 183-21) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380470 (US9926306, ID 187-23) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.36 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380471 (US9926306, ID 183-81) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380472 (US9926306, ID 187-39) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380473 (US9926306, ID 183-85) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380474 (US9926306, ID 178-97) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380475 (US9926306, ID 183-76) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380476 (US9926306, ID 183-91) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11.8 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380477 (US9926306, ID 183-38) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380478 (US9926306, ID 183-84) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380479 (US9926306, ID 187-82) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13.3 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380481 (US9926306, ID 183-24) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380480 (US9926306, ID 178-72) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380482 (US9926306, ID 183-65) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 17.7 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380443 (US9926306, ID 187-7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380450 (US9926306, ID 183-87) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380451 (US9926306, ID 183-44) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380452 (US9926306, ID 187-44) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238185 (US9394303, 57) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | 130 | -9.39 | 670 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380453 (US9926306, ID 183-89) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380454 (US9926306, ID 187-19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 891 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380455 (US9926306, ID 178-83) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM380456 (US9926306, ID 183-82 | US9926306, ID 187-79) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 937 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. | Assay Description A high-throughput competitive fluorescence polarization (FP) screening assay (Z-factor, 0.62) was developed based on the direct binding interaction b... | Bioorg Med Chem Lett 18: 2793-8 (2008) BindingDB Entry DOI: 10.7270/Q2QV3PTX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238190 (US9394303, 16) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 210 | -9.10 | 1.11E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238186 (US9394303, 58) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 250 | -9.00 | 1.28E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238181 (US9394303, 8) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 290 | -8.91 | 1.52E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238192 (US9394303, 18) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 490 | -8.60 | 2.54E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238187 (US9394303, 59) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 820 | -8.30 | 4.27E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238196 (US9394303, 62) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 880 | -8.26 | 4.51E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238184 (US9394303, 56) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 900 | -8.24 | 4.68E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238191 (US9394303, 17) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.21E+3 | -8.07 | 6.30E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM50318189 ((Z)-2-(3-((7-(2-Methoxyphenyl)-9-oxo-5H-benzo[h]th...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay | J Med Chem 53: 3465-79 (2010) Article DOI: 10.1021/jm901004c BindingDB Entry DOI: 10.7270/Q2QF8T11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238195 (US9394303, 61) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.30E+3 | -8.02 | 6.76E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238180 (US9394303, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.40E+3 | -7.98 | 7.30E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238182 (US9394303, 9) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.40E+3 | -7.98 | 7.30E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM238194 (US9394303, 60) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.53E+3 | -7.93 | 7.97E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent | Assay Description Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t... | US Patent US9394303 (2016) BindingDB Entry DOI: 10.7270/Q2RJ4HCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM50318190 ((Z)-3-((2-Methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Displacement of FITC-labeled BH3 peptide from GST-tagged mouse Mcl1 after 1 hr by fluorescence polarization assay | J Med Chem 53: 3465-79 (2010) Article DOI: 10.1021/jm901004c BindingDB Entry DOI: 10.7270/Q2QF8T11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Mus musculus (Mouse)) | BDBM50266967 (CHEBI:66678 | CHEMBL3393621) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged mouse Mcl-1 expressed in Escherichia coli BL21 (DE3) pre-incubated for 1 hr followed... | J Med Chem 60: 821-838 (2017) Article DOI: 10.1021/acs.jmedchem.5b01888 BindingDB Entry DOI: 10.7270/Q2ZC85BP | |||||||||||
More data for this Ligand-Target Pair |
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