Compile Data Set for Download or QSAR

Found 12 hits of ic50 for UniProtKB: P35375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190573 (US9181187, Compound K) Show SMILES CC(C)N(c1cc(C)c(C)cc1OCc1ccc(cc1Cl)-c1nnn[nH]1)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C24H25ClN6O3S/c1-15(2)31(35(32,33)20-6-5-9-26-13-20)22-10-16(3)17(4)11-23(22)34-14-19-8-7-18(12-21(19)25)24-27-29-30-28-24/h5-13,15H,14H2,1-4H3,(H,27,28,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190568 (US9181187, Compound F) Show SMILES CC(C)CN(c1cc2CCCc2cc1OCc1ccc(cc1C)C(O)=O)S(=O)(=O)c1ccc(C)o1 Show InChI InChI=1S/C27H31NO6S/c1-17(2)15-28(35(31,32)26-11-8-19(4)34-26)24-13-20-6-5-7-21(20)14-25(24)33-16-23-10-9-22(27(29)30)12-18(23)3/h8-14,17H,5-7,15-16H2,1-4H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190572 (US9181187, Compound J) Show SMILES CC(C)N(c1cc(C)c(Cl)cc1OCc1ccc(cc1C)-c1nnn[nH]1)S(=O)(=O)c1nc(C)cs1 Show InChI InChI=1S/C23H25ClN6O3S2/c1-13(2)30(35(31,32)23-25-16(5)12-34-23)20-9-15(4)19(24)10-21(20)33-11-18-7-6-17(8-14(18)3)22-26-28-29-27-22/h6-10,12-13H,11H2,1-5H3,(H,26,27,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190563 (US9181187, Compound A) Show SMILES CC(C)CN(c1cc2CCCc2cc1OCc1ccc(cc1C)C(O)=O)S(=O)(=O)c1nccs1 Show InChI InChI=1S/C25H28N2O5S2/c1-16(2)14-27(34(30,31)25-26-9-10-33-25)22-12-18-5-4-6-19(18)13-23(22)32-15-21-8-7-20(24(28)29)11-17(21)3/h7-13,16H,4-6,14-15H2,1-3H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190574 (US9181187, Compound L) Show SMILES CC(C)N(c1cc(C)c(C)cc1OCc1ccc(cc1)-c1noc(=O)[nH]1)S(=O)(=O)c1nc(C)cs1 Show InChI InChI=1S/C24H26N4O5S2/c1-14(2)28(35(30,31)24-25-17(5)13-34-24)20-10-15(3)16(4)11-21(20)32-12-18-6-8-19(9-7-18)22-26-23(29)33-27-22/h6-11,13-14H,12H2,1-5H3,(H,26,27,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190566 (US9181187, Compound D) Show SMILES CC(C)CN(c1cc(C)c(C)cc1OCc1ccc(cc1)C(O)=O)S(=O)(=O)c1ccc(C)o1 Show InChI InChI=1S/C25H29NO6S/c1-16(2)14-26(33(29,30)24-11-6-19(5)32-24)22-12-17(3)18(4)13-23(22)31-15-20-7-9-21(10-8-20)25(27)28/h6-13,16H,14-15H2,1-5H3,(H,27,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190570 (US9181187, Compound H) Show SMILES CC(C)CN(c1cc(C)c(C)cc1OCc1ccc(cc1C)C(O)=O)S(=O)(=O)c1ccccn1 Show InChI InChI=1S/C26H30N2O5S/c1-17(2)15-28(34(31,32)25-8-6-7-11-27-25)23-13-18(3)19(4)14-24(23)33-16-22-10-9-21(26(29)30)12-20(22)5/h6-14,17H,15-16H2,1-5H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190565 (US9181187, Compound C) Show SMILES CC(C)CN(c1cc(C)c(C)cc1OCc1ccc(cc1C)C(O)=O)S(=O)(=O)c1ccc(C)o1 Show InChI InChI=1S/C26H31NO6S/c1-16(2)14-27(34(30,31)25-10-7-20(6)33-25)23-12-17(3)18(4)13-24(23)32-15-22-9-8-21(26(28)29)11-19(22)5/h7-13,16H,14-15H2,1-6H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190571 (US9181187, Compound I) Show SMILES CC(C)CN(c1cc(C)c(C)cc1OCc1ccc(\C=C\C(O)=O)cc1C)S(=O)(=O)c1cccnc1 Show InChI InChI=1S/C28H32N2O5S/c1-19(2)17-30(36(33,34)25-7-6-12-29-16-25)26-14-20(3)21(4)15-27(26)35-18-24-10-8-23(13-22(24)5)9-11-28(31)32/h6-16,19H,17-18H2,1-5H3,(H,31,32)/b11-9+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190564 (US9181187, Compound B) Show SMILES CC(C)CN(c1cc2CCCc2cc1OCc1ccc(cc1)C(O)=O)S(=O)(=O)c1nc(C)cs1 Show InChI InChI=1S/C25H28N2O5S2/c1-16(2)13-27(34(30,31)25-26-17(3)15-33-25)22-11-20-5-4-6-21(20)12-23(22)32-14-18-7-9-19(10-8-18)24(28)29/h7-12,15-16H,4-6,13-14H2,1-3H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190567 (US9181187, Compound E) Show SMILES CC(C)CN(c1cc2CCCc2cc1OCc1ccc(\C=C\C(O)=O)cc1)S(=O)(=O)c1ccc(C)o1 Show InChI InChI=1S/C28H31NO6S/c1-19(2)17-29(36(32,33)28-14-7-20(3)35-28)25-15-23-5-4-6-24(23)16-26(25)34-18-22-10-8-21(9-11-22)12-13-27(30)31/h7-16,19H,4-6,17-18H2,1-3H3,(H,30,31)/b13-12+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM190569 (US9181187, Compound G) Show SMILES CC(C)CN(c1ccc(cc1OCc1ccc(\C=C\C(O)=O)cc1)C(F)(F)F)S(=O)(=O)c1nc(C)cs1 Show InChI InChI=1S/C25H25F3N2O5S2/c1-16(2)13-30(37(33,34)24-29-17(3)15-36-24)21-10-9-20(25(26,27)28)12-22(21)35-14-19-6-4-18(5-7-19)8-11-23(31)32/h4-12,15-16H,13-14H2,1-3H3,(H,31,32)/b11-8+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	37
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...				US Patent US9181187 (2015) BindingDB Entry DOI: 10.7270/Q2JM28D7
					More data for this Ligand-Target Pair