Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50436040 (CHEMBL2392184) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Curated by ChEMBL | Assay Description Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co... | J Med Chem 56: 5198-202 (2013) Article DOI: 10.1021/jm3018628 BindingDB Entry DOI: 10.7270/Q2VM4DNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50436040 (CHEMBL2392184) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Curated by ChEMBL | Assay Description Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co... | J Med Chem 56: 5198-202 (2013) Article DOI: 10.1021/jm3018628 BindingDB Entry DOI: 10.7270/Q2VM4DNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50158852 (CHEMBL3785340) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Competitive inhibition of recombinant His6-tagged KDM2A (1 to 517 residues) (unknown origin) expressed in Escherichia coli BL21 cells using methylsta... | J Med Chem 59: 1308-29 (2016) Article DOI: 10.1021/acs.jmedchem.5b01758 BindingDB Entry DOI: 10.7270/Q2MP5559 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50158851 (CHEMBL3786265) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Competitive inhibition of recombinant His6-tagged KDM2A (1 to 517 residues) (unknown origin) expressed in Escherichia coli BL21 cells using methylsta... | J Med Chem 59: 1308-29 (2016) Article DOI: 10.1021/acs.jmedchem.5b01758 BindingDB Entry DOI: 10.7270/Q2MP5559 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50158853 (CHEMBL3786188) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Competitive inhibition of recombinant His6-tagged KDM2A (1 to 517 residues) (unknown origin) expressed in Escherichia coli BL21 cells using methylsta... | J Med Chem 59: 1308-29 (2016) Article DOI: 10.1021/acs.jmedchem.5b01758 BindingDB Entry DOI: 10.7270/Q2MP5559 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Competitive inhibition of human KDM2A expressed in Escherichia coli using 2-oxoglutarate by enzyme kinetic assay | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50436040 (CHEMBL2392184) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Curated by ChEMBL | Assay Description Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co... | J Med Chem 56: 5198-202 (2013) Article DOI: 10.1021/jm3018628 BindingDB Entry DOI: 10.7270/Q2VM4DNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50436040 (CHEMBL2392184) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Curated by ChEMBL | Assay Description Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co... | J Med Chem 56: 5198-202 (2013) Article DOI: 10.1021/jm3018628 BindingDB Entry DOI: 10.7270/Q2VM4DNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50436040 (CHEMBL2392184) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Colorado Curated by ChEMBL | Assay Description Competitive binding affinity to recombinant 6xHis-tagged JHDM1A (unknown origin) expressed in Escherichia coli BL21 incubated for 30 mins prior to co... | J Med Chem 56: 5198-202 (2013) Article DOI: 10.1021/jm3018628 BindingDB Entry DOI: 10.7270/Q2VM4DNK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 2A (Homo sapiens (Human)) | BDBM50395076 (CHEMBL2164243) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Mixed type inhibition of human KDM2A expressed in Escherichia coli assessed inhibition constant for compound-enzyme-substrate complex using methyl ly... | J Med Chem 55: 6639-43 (2012) Article DOI: 10.1021/jm300677j BindingDB Entry DOI: 10.7270/Q2JH3N9S | |||||||||||
More data for this Ligand-Target Pair |