Compile Data Set for Download or QSAR

Found 9 hits of ec50 for UniProtKB: P63251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM34572 (BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 |t:4| Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.0372	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM10759 (2-acetoxyethyl(trimethyl)ammonium;bromide | 2-acet...) Show SMILES CC(=O)OCC[N+](C)(C)C Show InChI InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.0614	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM73209 ((+)-CIS-DIOXOLANE | CHEMBL105457 | MLS000069362 | ...) Show SMILES C[C@H]1OC[C@@H](C[N+](C)(C)C)O1 Show InChI InChI=1S/C8H18NO2/c1-7-10-6-8(11-7)5-9(2,3)4/h7-8H,5-6H2,1-4H3/q+1/t7-,8+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.280	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM73210 ((5Z)-5-{(2E)-3-[4-(dimethylamino)phenyl]-1-hydroxy...) Show SMILES [H]C12CC(C)(Oc3ccccc13)N(C)C(O)=C2C(=O)\C=C\c1ccc(cc1)N(C)C |c:17,TLB:13:12:2:5.11.6,THB:10:11:2:12.16.14,17:16:2:5.11.6| Show InChI InChI=1S/C24H26N2O3/c1-24-15-19(18-7-5-6-8-21(18)29-24)22(23(28)26(24)4)20(27)14-11-16-9-12-17(13-10-16)25(2)3/h5-14,19,28H,15H2,1-4H3/b14-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	0.856	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM50004233 (5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...) Show SMILES Cc1c2[nH]c3ccccc3c2c(C)c2cnccc12 Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.49	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21G0JR7
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM73211 (1-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)-3-[1,1,1...) Show SMILES CCSc1nnc(NC(=O)NC(CC)(C(F)(F)F)C(F)(F)F)s1 Show InChI InChI=1S/C10H12F6N4OS2/c1-3-8(9(11,12)13,10(14,15)16)18-5(21)17-6-19-20-7(23-6)22-4-2/h3-4H2,1-2H3,(H2,17,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WQ028B
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM42613 (3-allyl-2-thioxo-1H-quinazolin-4-one | 3-prop-2-en...) Show SMILES C=CCn1c(=S)[nH]c2ccccc2c1=O Show InChI InChI=1S/C11H10N2OS/c1-2-7-13-10(14)8-5-3-4-6-9(8)12-11(13)15/h2-6H,1,7H2,(H,12,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	PCBioAssay	n/a	n/a	n/a	n/a	3.15E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WQ028B
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM36882 (3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-bis(oxida...) Show SMILES Oc1cc(O)c2c(c1)oc(c(-c1ccc3OCCOc3c1)c2=O)C(F)(F)F Show InChI InChI=1S/C18H11F3O6/c19-18(20,21)17-14(8-1-2-11-12(5-8)26-4-3-25-11)16(24)15-10(23)6-9(22)7-13(15)27-17/h1-2,5-7,22-23H,3-4H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WQ028B
					More data for this Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1 (Rattus norvegicus)	BDBM73212 (4-[1-(tetrahydrofuryl)ethylcarbamoylamino]benzoic ...) Show SMILES CCOC(=O)c1ccc(NC(=O)NC(C)C2CCCO2)cc1 Show InChI InChI=1S/C16H22N2O4/c1-3-21-15(19)12-6-8-13(9-7-12)18-16(20)17-11(2)14-5-4-10-22-14/h6-9,11,14H,3-5,10H2,1-2H3,(H2,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	4.14E+4	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2WQ028B
					More data for this Ligand-Target Pair