Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50343785 (CHEMBL1774386 | N-(4-(4-(2,3-Dichlorophenyl)pipera...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to wild type human dopamine D3 receptor expressed in HEK293 cells | J Med Chem 54: 3581-94 (2011) Article DOI: 10.1021/jm200288r BindingDB Entry DOI: 10.7270/Q25M661K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50336701 ((6aR,9R)-N-((2S)-1-((2S)-1-(3-(6-((S)-6-amino-6-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-raclopride from human dopamine D3 receptor high binding affinity site expressed in CHO cells | J Med Chem 54: 1080-90 (2011) Article DOI: 10.1021/jm101566d BindingDB Entry DOI: 10.7270/Q2QF8T5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50336701 ((6aR,9R)-N-((2S)-1-((2S)-1-(3-(6-((S)-6-amino-6-ox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-raclopride from human dopamine D3 receptor low binding affinity site expressed in CHO cells | J Med Chem 54: 1080-90 (2011) Article DOI: 10.1021/jm101566d BindingDB Entry DOI: 10.7270/Q2QF8T5T | |||||||||||
More data for this Ligand-Target Pair |