Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuromedin-K receptor (GUINEA PIG) | BDBM50299467 ((5S,8S,14S,17S,20S,23S,26S,29S,32S)-26-((1H-imidaz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Agonist activity at guinea pig NK3 receptor expressed in cells assessed as accumulation of [3H]inositol phosphate | J Med Chem 52: 7103-12 (2009) Article DOI: 10.1021/jm900948q BindingDB Entry DOI: 10.7270/Q21G0MBP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-K receptor (GUINEA PIG) | BDBM50007962 (CHEMBL81919 | pGlu6-Phe-NMePhe-Gly-Leu-Met-NH2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a |
Hebrew University of Jerusalem Curated by ChEMBL | Assay Description Effective dose of the compound was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methy... | J Med Chem 34: 2430-8 (1991) BindingDB Entry DOI: 10.7270/Q2P55MFQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-K receptor (GUINEA PIG) | BDBM50007963 (CHEMBL441061 | pGlu6-Phe-Phe-Gly-Leu-Met-NH2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Hebrew University of Jerusalem Curated by ChEMBL | Assay Description Effective dose of the compound was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methy... | J Med Chem 34: 2430-8 (1991) BindingDB Entry DOI: 10.7270/Q2P55MFQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-K receptor (GUINEA PIG) | BDBM50007972 (CHEMBL311917 | pGlu6-Phe-Phe8(psi)CH2O-Gly-Leu-Met...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Hebrew University of Jerusalem Curated by ChEMBL | Assay Description Effective dose of the compound was measured on NK3 receptors of guinea pig ileum for maximal contraction in the presence of 10e-7 M substance P methy... | J Med Chem 34: 2430-8 (1991) BindingDB Entry DOI: 10.7270/Q2P55MFQ | |||||||||||
More data for this Ligand-Target Pair |