Found 6 hits of kd data for polymerid = 49001069,49001070 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Urotensin-2 receptor
(Homo sapiens (Human)) | BDBM50412075
(CHEMBL404177)Show SMILES Clc1ccc2scc(CC(=O)N3CCC[C@@H]([C@@H]3CN3CCCC3)c3ccccc3)c2c1 Show InChI InChI=1S/C26H29ClN2OS/c27-21-10-11-25-23(16-21)20(18-31-25)15-26(30)29-14-6-9-22(19-7-2-1-3-8-19)24(29)17-28-12-4-5-13-28/h1-3,7-8,10-11,16,18,22,24H,4-6,9,12-15,17H2/t22-,24+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human urotensin 2 receptor |
Bioorg Med Chem Lett 18: 2860-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.078 BindingDB Entry DOI: 10.7270/Q29S1RXX |
More data for this Ligand-Target Pair | |
Urotensin-2 receptor
(Homo sapiens (Human)) | BDBM50413017
(CHEMBL500880)Show InChI InChI=1S/C18H15N3/c1-2-6-13(7-3-1)12-20-18-17-14-8-4-5-9-15(14)21-16(17)10-11-19-18/h1-11,21H,12H2,(H,19,20) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human urotensin 2 receptor by FLIPR assay |
Bioorg Med Chem Lett 18: 4936-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.054 BindingDB Entry DOI: 10.7270/Q2GH9K5T |
More data for this Ligand-Target Pair | |
Urotensin-2 receptor
(Homo sapiens (Human)) | BDBM50413014
(CHEMBL497171)Show InChI InChI=1S/C15H17N3/c1-2-3-9-16-15-14-11-6-4-5-7-12(11)18-13(14)8-10-17-15/h4-8,10,18H,2-3,9H2,1H3,(H,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human urotensin 2 receptor by FLIPR assay |
Bioorg Med Chem Lett 18: 4936-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.054 BindingDB Entry DOI: 10.7270/Q2GH9K5T |
More data for this Ligand-Target Pair | |
Urotensin-2 receptor
(Homo sapiens (Human)) | BDBM50413020
(CHEMBL523566)Show InChI InChI=1S/C16H19N3/c1-3-11(2)10-18-16-15-12-6-4-5-7-13(12)19-14(15)8-9-17-16/h4-9,11,19H,3,10H2,1-2H3,(H,17,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human urotensin 2 receptor by FLIPR assay |
Bioorg Med Chem Lett 18: 4936-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.054 BindingDB Entry DOI: 10.7270/Q2GH9K5T |
More data for this Ligand-Target Pair | |
Urotensin-2 receptor
(Homo sapiens (Human)) | BDBM50413018
(CHEMBL497561)Show InChI InChI=1S/C15H15N3/c1-2-4-12-11(3-1)14-13(18-12)7-8-16-15(14)17-9-10-5-6-10/h1-4,7-8,10,18H,5-6,9H2,(H,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human urotensin 2 receptor by FLIPR assay |
Bioorg Med Chem Lett 18: 4936-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.054 BindingDB Entry DOI: 10.7270/Q2GH9K5T |
More data for this Ligand-Target Pair | |
Urotensin-2 receptor
(Homo sapiens (Human)) | BDBM50413016
(CHEMBL496516)Show InChI InChI=1S/C16H13N3S/c1-2-6-13-12(5-1)15-14(19-13)7-8-17-16(15)18-10-11-4-3-9-20-11/h1-9,19H,10H2,(H,17,18) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Antagonist activity at human urotensin 2 receptor by FLIPR assay |
Bioorg Med Chem Lett 18: 4936-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.054 BindingDB Entry DOI: 10.7270/Q2GH9K5T |
More data for this Ligand-Target Pair | |