Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50503849 (CHEMBL4590466) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc... | Bioorg Med Chem 27: 436-441 (2019) Article DOI: 10.1016/j.bmc.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189833 ((S)-N-butyl-3-((S)-2-(4-fluorophenylsulfonamido)-3...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50503846 (CHEMBL4540394) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc... | Bioorg Med Chem 27: 436-441 (2019) Article DOI: 10.1016/j.bmc.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50503847 (CHEMBL4574306) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc... | Bioorg Med Chem 27: 436-441 (2019) Article DOI: 10.1016/j.bmc.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50114340 ((S)-2-(4-Fluoro-benzenesulfonylamino)-N-((S)-1-for...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50263559 (((1S)-1-((((1S)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2,3-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of pig kidney m-calpain | Bioorg Med Chem Lett 18: 5174-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.089 BindingDB Entry DOI: 10.7270/Q2P55NBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50263560 (2-methoxyethyl (S)-1-((S)-4-(cyclopropylamino)-3,4...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of pig kidney m-calpain | Bioorg Med Chem Lett 18: 5174-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.089 BindingDB Entry DOI: 10.7270/Q2P55NBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189825 ((2S)-2-((((4-cyanophenyl)amino)thioxomethyl)amino)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50263561 (2-(2-(2-methoxyethoxy)ethoxy)ethyl (S)-1-((S)-4-(c...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of pig kidney m-calpain | Bioorg Med Chem Lett 18: 5174-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.089 BindingDB Entry DOI: 10.7270/Q2P55NBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50503845 (CHEMBL4531762) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc... | Bioorg Med Chem 27: 436-441 (2019) Article DOI: 10.1016/j.bmc.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189834 ((2S)-2-((((3-cyanophenyl)amino)thioxomethyl)amino)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189832 ((2S)-4-methyl-2-((((4-methylphenyl)amino)thioxomet...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50263613 (2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethyl (S)-1...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of pig kidney m-calpain | Bioorg Med Chem Lett 18: 5174-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.089 BindingDB Entry DOI: 10.7270/Q2P55NBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50263558 (2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)e...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of pig kidney m-calpain | Bioorg Med Chem Lett 18: 5174-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.089 BindingDB Entry DOI: 10.7270/Q2P55NBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189835 ((2S)-2-((((4-fluorophenyl)amino)thioxomethyl)amino...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189828 (1-((S)-1-((3S)-2-hydroxy-tetrahydrofuran-3-ylamino...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189827 ((2S)-2-((((4-methoxyphenyl)amino)thioxomethyl)amin...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189822 ((2S)-2-((benzylamino)thioxomethyl)amino)-4-methyl-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189830 ((2S)-4-methyl-2-((((2-methylphenyl)amino)thioxomet...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189831 ((2S)-4-methyl-2-((((3-methylphenyl)amino)thioxomet...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189823 ((2S,3S)-3-methyl-2-(((phenylamino)thioxomethyl)ami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189829 ((2S)-3-methyl-2-(((phenylamino)thioxomethyl)amino)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189826 ((S)-2-(4-fluorophenylsulfonamido)-N-((3S)-2-hydrox...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50503848 (CHEMBL4475662) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide Curated by ChEMBL | Assay Description Inhibition of recombinant porcine calpain 2 protease using BODIPY-FL casein as substrate measured at 30 secs time interval for 30 mins by fluorescenc... | Bioorg Med Chem 27: 436-441 (2019) Article DOI: 10.1016/j.bmc.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27P1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-2 catalytic subunit (Sus scrofa) | BDBM50189824 (CHEMBL206737 | N-(1-cyano-3-methylbutyl)-2-((4-flu...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Senju Pharmaceutical Company, Ltd. Curated by ChEMBL | Assay Description Inhibition of porcein kidney m calpain | J Med Chem 49: 3926-32 (2006) Article DOI: 10.1021/jm060157n BindingDB Entry DOI: 10.7270/Q21R6Q48 | |||||||||||
More data for this Ligand-Target Pair |