Compile Data Set for Download or QSAR

Found 10 hits of ic50 for UniProtKB: P06987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486978 (CHEMBL49183) Show SMILES O=Cc1[nH]c(C(=O)OCc2ccccc2)c(Cc2ccccc2)c1Cc1ccccc1 Show InChI InChI=1S/C27H23NO3/c29-18-25-23(16-20-10-4-1-5-11-20)24(17-21-12-6-2-7-13-21)26(28-25)27(30)31-19-22-14-8-3-9-15-22/h1-15,18,28H,16-17,19H2	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM15011 (2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicar...) Show SMILES CCOC(=O)c1[nH]c(C=O)c(C(=O)OCC)c1C Show InChI InChI=1S/C12H15NO5/c1-4-17-11(15)9-7(3)10(12(16)18-5-2)13-8(9)6-14/h6,13H,4-5H2,1-3H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM15012 (2,4-diethyl 3-ethyl-5-formyl-1H-pyrrole-2,4-dicarb...) Show SMILES CCOC(=O)c1[nH]c(C=O)c(C(=O)OCC)c1CC Show InChI InChI=1S/C13H17NO5/c1-4-8-10(12(16)18-5-2)9(7-15)14-11(8)13(17)19-6-3/h7,14H,4-6H2,1-3H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486983 (CHEMBL48293) Show SMILES Cc1c(C)c(C=O)[nH]c1C=O Show InChI InChI=1S/C8H9NO2/c1-5-6(2)8(4-11)9-7(5)3-10/h3-4,9H,1-2H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486985 (CHEMBL48733) Show SMILES COC(=O)c1[nH]c(C=O)c(C(=O)OC)c1C(C)C Show InChI InChI=1S/C12H15NO5/c1-6(2)8-9(11(15)17-3)7(5-14)13-10(8)12(16)18-4/h5-6,13H,1-4H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486979 (CHEMBL296835) Show SMILES Cc1c(C)c([nH]c1C=O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C15H15NO3/c1-10-11(2)14(16-13(10)8-17)15(18)19-9-12-6-4-3-5-7-12/h3-8,16H,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486984 (CHEMBL299092) Show SMILES CCOC(=O)c1[nH]c(C=O)cc1C Show InChI InChI=1S/C9H11NO3/c1-3-13-9(12)8-6(2)4-7(5-11)10-8/h4-5,10H,3H2,1-2H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486980 (CHEMBL410501) Show SMILES CCOCC(=O)Cc1c(CCC(=O)OCC)c([nH]c1C=O)C(=O)OCC Show InChI InChI=1S/C18H25NO7/c1-4-24-11-12(21)9-14-13(7-8-16(22)25-5-2)17(18(23)26-6-3)19-15(14)10-20/h10,19H,4-9,11H2,1-3H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486981 (CHEMBL298963) Show SMILES CCOC(=O)c1[nH]c(C=O)c(C)c1C Show InChI InChI=1S/C10H13NO3/c1-4-14-10(13)9-7(3)6(2)8(5-12)11-9/h5,11H,4H2,1-3H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair
Histidine biosynthesis bifunctional protein HisB (Escherichia coli (strain K12))	BDBM50486982 (CHEMBL296253) Show SMILES CCc1c(C)c([nH]c1C=O)C(=O)OCc1ccccc1 Show InChI InChI=1S/C16H17NO3/c1-3-13-11(2)15(17-14(13)9-18)16(19)20-10-12-7-5-4-6-8-12/h4-9,17H,3,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Monsanto Company Curated by ChEMBL					Assay Description Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...				Bioorg Med Chem Lett 12: 1743-6 (2002) Article DOI: 10.1016/s0960-894x(02)00283-4 BindingDB Entry DOI: 10.7270/Q2P55RDX
					More data for this Ligand-Target Pair