Compile Data Set for Download or QSAR

Found 5 hits of kd for UniProtKB: P23921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50247408 (CHEMBL4067105) Show SMILES Oc1ccccc1C(=O)N\N=C\c1c(O)ccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c21-16-8-4-3-7-14(16)18(23)20-19-11-15-13-6-2-1-5-12(13)9-10-17(15)22/h1-11,21-22H,(H,20,23)/b19-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Binding affinity to human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL by fluorescence spectrophotometric method				J Med Chem 61: 666-680 (2018) Article DOI: 10.1021/acs.jmedchem.7b00530 BindingDB Entry DOI: 10.7270/Q2W098CB
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50500165 (CHEMBL3746526) Show SMILES CCCOc1ccc(cc1NS(=O)(=O)\C=C\c1ccccc1)C(=O)OCCN(CC)CC Show InChI InChI=1S/C24H32N2O5S/c1-4-16-30-23-13-12-21(24(27)31-17-15-26(5-2)6-3)19-22(23)25-32(28,29)18-14-20-10-8-7-9-11-20/h7-14,18-19,25H,4-6,15-17H2,1-3H3/b18-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.53E+4	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assay				J Med Chem 58: 9498-509 (2015) Article DOI: 10.1021/acs.jmedchem.5b00929 BindingDB Entry DOI: 10.7270/Q2MW2M5M
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50500166 (CHEMBL3747319) Show SMILES CC(NCCCCCO)c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1 Show InChI InChI=1S/C27H33NO3/c1-22(28-15-9-4-10-16-29)25-17-26(30-20-23-11-5-2-6-12-23)19-27(18-25)31-21-24-13-7-3-8-14-24/h2-3,5-8,11-14,17-19,22,28-29H,4,9-10,15-16,20-21H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assay				J Med Chem 58: 9498-509 (2015) Article DOI: 10.1021/acs.jmedchem.5b00929 BindingDB Entry DOI: 10.7270/Q2MW2M5M
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50500171 (CHEMBL600902 | GNF-Pf-721) Show SMILES OC(COc1ccc(OCC(O)CN2CCN(CC2)C2c3ccccc3-c3ccccc23)cc1)CN1CCN(CC1)C1c2ccccc2-c2ccccc12 Show InChI InChI=1S/C46H50N4O4/c51-33(29-47-21-25-49(26-22-47)45-41-13-5-1-9-37(41)38-10-2-6-14-42(38)45)31-53-35-17-19-36(20-18-35)54-32-34(52)30-48-23-27-50(28-24-48)46-43-15-7-3-11-39(43)40-12-4-8-16-44(40)46/h1-20,33-34,45-46,51-52H,21-32H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.56E+4	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assay				J Med Chem 58: 9498-509 (2015) Article DOI: 10.1021/acs.jmedchem.5b00929 BindingDB Entry DOI: 10.7270/Q2MW2M5M
					More data for this Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit (Homo sapiens (Human))	BDBM50500168 (CHEMBL3746072) Show SMILES CC(C)(NC(=O)CN1C(=O)c2ccccc2C1=O)C(=O)NCCCC[C@H](NC(=O)CC(O)(C(F)(F)F)C(F)(F)F)C(O)=O |r| Show InChI InChI=1S/C25H28F6N4O8/c1-22(2,34-17(37)12-35-18(38)13-7-3-4-8-14(13)19(35)39)21(42)32-10-6-5-9-15(20(40)41)33-16(36)11-23(43,24(26,27)28)25(29,30)31/h3-4,7-8,15,43H,5-6,9-12H2,1-2H3,(H,32,42)(H,33,36)(H,34,37)(H,40,41)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	9.68E+3	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assay				J Med Chem 58: 9498-509 (2015) Article DOI: 10.1021/acs.jmedchem.5b00929 BindingDB Entry DOI: 10.7270/Q2MW2M5M
					More data for this Ligand-Target Pair