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Compile Data Set for Download or QSAR

Found 2 hits of ki for UniProtKB: P23921   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribonucleoside-diphosphate reductase large subunit


(Homo sapiens (Human))
BDBM50247408
PNG
(CHEMBL4067105)
Show SMILES Oc1ccccc1C(=O)N\N=C\c1c(O)ccc2ccccc12
Show InChI InChI=1S/C18H14N2O3/c21-16-8-4-3-7-14(16)18(23)20-19-11-15-13-6-2-1-5-12(13)9-10-17(15)22/h1-11,21-22H,(H,20,23)/b19-11+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
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MCE
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.00E+3n/an/an/an/an/an/an/an/a



Case Western Reserve University

Curated by ChEMBL


Assay Description
Competitive inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate


J Med Chem 61: 666-680 (2018)


Article DOI: 10.1021/acs.jmedchem.7b00530
BindingDB Entry DOI: 10.7270/Q2W098CB
More data for this
Ligand-Target Pair
Ribonucleoside-diphosphate reductase large subunit/subunit M2 B


(Homo sapiens (Human))
BDBM50497567
PNG
(CHEMBL3337770)
Show SMILES CCCC(CCC)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@]1(C)O)n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C19H29N5O5/c1-4-6-11(7-5-2)18(26)28-8-12-19(3,27)14(25)17(29-12)24-10-23-13-15(20)21-9-22-16(13)24/h9-12,14,17,25,27H,4-8H2,1-3H3,(H2,20,21,22)/t12-,14+,17-,19-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
4.00E+5n/an/an/an/an/an/an/an/a



University of Camerino

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant ribonucleotide reductase in presence of varying levels of ATP by Dixon plot


Bioorg Med Chem Lett 24: 5304-9 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.046
BindingDB Entry DOI: 10.7270/Q22Z18H9
More data for this
Ligand-Target Pair