Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription factor 4 (Homo sapiens) | BDBM50436058 (CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomach | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor 4 (Homo sapiens) | BDBM50436058 (CHEMBL254381 | PNU-74654 | US9738628, Compound PNU...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a |
King Saud University Curated by ChEMBL | Assay Description Inhibition of His6 tagged Tcf4 1-53/beta catenin (unknown origin) interaction by VP-ITC titration calorimeter method | Bioorg Med Chem Lett 26: 1664-70 (2016) Article DOI: 10.1016/j.bmcl.2016.02.064 BindingDB Entry DOI: 10.7270/Q25H7K8M | |||||||||||
More data for this Ligand-Target Pair |