Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 6 (Homo sapiens) | BDBM50538571 (CHEMBL4635160) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of human GST-tagged USP6 CD (529 to 1406 residues) expressed in Sf21 insect cells assessed as cleavage of Ubiquitin-Rhodamine110-glycine t... | J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T | |||||||||||
More data for this Ligand-Target Pair |