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Compile Data Set for Download or QSAR

Found 1 hit of kd for UniProtKB: P07992   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA excision repair protein ERCC-1/repair endonuclease XPF


(Homo sapiens)		BDBM50504115
PNG
(CHEMBL4470176)
Show SMILES COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(O)c(CN4CCN(CCN(C)C)CC4)c3)c2c1
Show InChI InChI=1S/C29H34ClN5O2/c1-33(2)10-11-34-12-14-35(15-13-34)19-20-16-22(5-9-28(20)36)31-29-24-7-4-21(30)17-27(24)32-26-8-6-23(37-3)18-25(26)29/h4-9,16-18,36H,10-15,19H2,1-3H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 100n/an/an/an/an/a



University of Alberta

Curated by ChEMBL


Assay Description
Binding affinity to human His6-tagged ERCC1-XPF expressed in Escherichia coli BL21 (DE3) by spectrofluorimetric method

J Med Chem 62: 7684-7696 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00326
BindingDB Entry DOI: 10.7270/Q2FX7DRF
More data for this
Ligand-Target Pair