Compile Data Set for Download or QSAR

Found 5 hits of ic50 for UniProtKB: P28301   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-lysine 6-oxidase (Mus musculus)	BDBM50526737 (CHEMBL4528500 | US10807974, Example 82 | US1099508...) Show SMILES Cc1ccc(cc1)-c1cc(ccc1S(C)(=O)=O)S(=O)(=O)c1ccc(CN)s1 Show InChI InChI=1S/C19H19NO4S3/c1-13-3-5-14(6-4-13)17-11-16(8-9-18(17)26(2,21)22)27(23,24)19-10-7-15(12-20)25-19/h3-11H,12,20H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<180	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Mus musculus)	BDBM50526721 (CHEMBL4444163 | US10807974, Example 111 | US109950...) Show SMILES CCc1cc(cc(c1)S(=O)(=O)c1cnc(CN)s1)-c1cnn(C)c1 Show InChI InChI=1S/C16H18N4O2S2/c1-3-11-4-12(13-8-19-20(2)10-13)6-14(5-11)24(21,22)16-9-18-15(7-17)23-16/h4-6,8-10H,3,7,17H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Mus musculus)	BDBM469107 (US10807974, Example 126 | US10995088, Example 126 ...) Show SMILES NCc1ncc(s1)S(=O)(=O)c1cc(cc(c1)-c1ccccc1)C(O)=O Show InChI InChI=1S/C17H14N2O4S2/c18-9-15-19-10-16(24-15)25(22,23)14-7-12(6-13(8-14)17(20)21)11-4-2-1-3-5-11/h1-8,10H,9,18H2,(H,20,21)	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Mus musculus)	BDBM50505638 (CHEMBL4457578) Show SMILES Cl.CN(C)S(=O)(=O)c1cccc(c1)-c1c(C)n(C\C(F)=C\CN)c2ccc(cc12)C(O)=O Show InChI InChI=1S/C22H24FN3O4S/c1-14-21(15-5-4-6-18(11-15)31(29,30)25(2)3)19-12-16(22(27)28)7-8-20(19)26(14)13-17(23)9-10-24/h4-9,11-12H,10,13,24H2,1-3H3,(H,27,28)/b17-9-	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaxis Ltd Curated by ChEMBL					Assay Description Inhibition of LOX in mouse lung fibroblast cells using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition an...				J Med Chem 62: 9874-9889 (2019) Article DOI: 10.1021/acs.jmedchem.9b01283 BindingDB Entry DOI: 10.7270/Q2VM4GJ2
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Mus musculus)	BDBM50501885 (CHEMBL4441173 | US10807974, Example 68 | US1099508...) Show SMILES CS(=O)(=O)c1cc(cc(c1)S(=O)(=O)c1ccc(CN)s1)-c1ccccc1 Show InChI InChI=1S/C18H17NO4S3/c1-25(20,21)16-9-14(13-5-3-2-4-6-13)10-17(11-16)26(22,23)18-8-7-15(12-19)24-18/h2-11H,12,19H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research: Royal Cancer Hospital US Patent					Assay Description To produce MDCK cysts, cells were cultured on Matrigel (Corning) with 2% Matrigel supplemented in DMEM with 10% FBS. Cysts were allowed to form for 1...				US Patent US10807974 (2020) BindingDB Entry DOI: 10.7270/Q2TH8QS8
					More data for this Ligand-Target Pair