Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 4F8 (Homo sapiens) | BDBM50527963 (CHEMBL4557940) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate preincubated with NAD... | J Med Chem 63: 4824-4836 (2020) Article DOI: 10.1021/acs.jmedchem.0c00101 BindingDB Entry DOI: 10.7270/Q2HT2SS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 4F8 (Homo sapiens) | BDBM50527963 (CHEMBL4557940) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate after 10 mins in pres... | J Med Chem 63: 4824-4836 (2020) Article DOI: 10.1021/acs.jmedchem.0c00101 BindingDB Entry DOI: 10.7270/Q2HT2SS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 4F8 (Homo sapiens) | BDBM50527962 (CHEMBL4442292) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate preincubated with NAD... | J Med Chem 63: 4824-4836 (2020) Article DOI: 10.1021/acs.jmedchem.0c00101 BindingDB Entry DOI: 10.7270/Q2HT2SS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 4F8 (Homo sapiens) | BDBM50527962 (CHEMBL4442292) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Curated by ChEMBL | Assay Description Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate after 10 mins in pres... | J Med Chem 63: 4824-4836 (2020) Article DOI: 10.1021/acs.jmedchem.0c00101 BindingDB Entry DOI: 10.7270/Q2HT2SS4 | |||||||||||
More data for this Ligand-Target Pair |