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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for UniProtKB: P84903   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium release-activated calcium channel protein/Stromal interaction molecule 1


(Rattus norvegicus)
BDBM50204544
PNG
(CHEMBL262766)
Show SMILES Cc1nnsc1C(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
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Article
PubMed
n/an/a 590n/an/an/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Inhibition of ORAI/STIM1 in thapsigargin treated rat RBL2H3 cells assessed as reduction in store-operated calcium entry after 5 mins by fura-2-AM dye...


J Med Chem 62: 7589-7602 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01954
BindingDB Entry DOI: 10.7270/Q2XS5ZR8
More data for this
Ligand-Target Pair