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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P01031   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement C5


(Homo sapiens)
BDBM50546241
PNG
(CHEMBL2203296)
Show SMILES CCCCCCOc1cc(NC(=O)N[C@@H](C)c2ccccc2)ccc1OC |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 210n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C5 complement protein in 2% human serum incubated for 15 mins


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b01033
BindingDB Entry DOI: 10.7270/Q2ZK5M83
More data for this
Ligand-Target Pair
Complement C5


(Homo sapiens)
BDBM50546240
PNG
(CHEMBL2204196)
Show SMILES COc1ccc(NC(=O)N[C@@H](C)c2ccccc2)cc1OCCCC(C)C |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 440n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C5 complement protein in 2% human serum incubated for 15 mins


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b01033
BindingDB Entry DOI: 10.7270/Q2ZK5M83
More data for this
Ligand-Target Pair
Complement C5


(Homo sapiens)
BDBM50546242
PNG
(CHEMBL4756677)
Show SMILES COc1cc(C(O)=O)c(NC(=O)N[C@@H](C)c2ccccc2)cc1OCCCC(C)C |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 620n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of C5 complement protein in 2% human serum incubated for 15 mins


Citation and Details

Article DOI: 10.1021/acs.jmedchem.9b01033
BindingDB Entry DOI: 10.7270/Q2ZK5M83
More data for this
Ligand-Target Pair